Results 111 to 120 of about 1,854,049 (378)

Hepcidin promotes oral ulcer healing via amphiregulin production in rats

Journal of Dental Sciences
Background/purpose: Hepcidin is an antimicrobial peptide that regulates iron metabolism. Recently, hepcidin was reported to promote wound healing. However, the mechanism underlying hepcidin signaling in the oral mucosa remains unclear.
Naoto Taguchi, Suzuro Hitomi, Hitoshi Sato, Yoshinori Hayashi, Ikuko Shibuta, Koichi Iwata, Tatsuo Shirota, Masamichi Shinoda   +7 more
doaj   +1 more source

First-in-Human Phase I Study to Evaluate the Brain-Penetrant PI3K/mTOR Inhibitor GDC-0084 in Patients with Progressive or Recurrent High-Grade Glioma. [PDF]

, 2020
PurposeGDC-0084 is an oral, brain-penetrant small-molecule inhibitor of PI3K and mTOR. A first-in-human, phase I study was conducted in patients with recurrent high-grade glioma.Patients and methodsGDC-0084 was administered orally, once daily, to ...
Cloughesy, Timothy F, Coimbra, Alexandre F, Ellingson, Benjamin M, Gerstner, Elizabeth, Lee, Eudocia Q, Lu, Xuyang, Morrissey, Kari M, Mueller, Lars U, Olivero, Alan G, Rodon, Jordi, Wen, Patrick Y, Wilson, Timothy R   +11 more
core  

Diagnostic accuracy of transmucosal probe visualization for peri‐implant mucosal phenotype assessment: A cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background This study evaluated the diagnostic accuracy of visual assessment of mucosal transparency using a standard periodontal probe (VAT) to differentiate between thin and thick peri‐implant mucosal phenotypes, compared to horizontal transmucosal probing (HTP).
Emilio Couso‐Queiruga, Manrique Fonseca, Diogo Moreira Rodrigues, Gustavo Avila‐Ortiz, Vivianne Chappuis, Clemens Raabe   +5 more
wiley   +1 more source

Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma [PDF]

, 2013
This study aimed at determining the recommended dose of the mammalian target of rapamycin inhibitor everolimus in combination with mitomycin C (MMC) in patients with previously treated metastatic esophagogastric cancer.
Atmaca, Akin, Batran, Salah-Eddin al-, Jäger, Elke, Pauligk, Claudia, Pustowka, Anette, Werner, Dominique   +5 more
core   +1 more source

Effects of an Oral Mucosa Protective Formulation on Chemotherapy- and/or Radiotherapy-induced Oral Mucositis: A Prospective Study [PDF]

, 2021
Takao Ueno, Wakako Yatsuoka, Hiroto Ishiki, Kanako Miyano, Yasuhito Uezono   +4 more
openalex   +1 more source

Unusual oral mucositis [PDF]

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2022
Tuomas Kakko, Jaana Hagström, Maria Siponen   +2 more
openaire   +2 more sources

Oral mucositis: recent perspectives on prevention and treatment [PDF]

, 2009
Oral mucositis is a result of toxicity and one of the most common side effects of radiotherapy and chemotherapy in cancer treatment and in hematopoietic stem cell transplantation.
Ana Cristina Messaggi, Andrea Mantesso, Marina Helena Cury Gallotini de Magalhães, Paulo Sérgio da Silva Santos   +3 more
core  

Influence of oral health on mucositis in patients undergoing hematopoietic progenitor cell transplantation (HPCT) [PDF]

, 2012
Aims: To establish whether or not the state of patient oral health can influence the occurrence and/or severity of oral mucositis during hematopoietic progenitor cell transplantation (HPCT).
Cabrerizo Merino, María del Carmen, de Arriba de la Fuente, Felipe, Heras, I., Hernández Fernández, Ana, Oñate Sánchez, Ricardo Elías, Vicente García, Vicente   +5 more
core   +1 more source

Oral mucosal melanoma [PDF]

Translational Research in Oral Oncology, 2017
Background: Oral mucosal melanoma (OMM) is relatively rare, runs an aggressive course, affects most frequently the hard palate and the maxillary gingiva, and may be multifocal. The aetiological factors and the chain of molecular events that give rise to OMM and to its growth and metastasis are largely unknown.
RAG Khammissa, M Altini, S Meer, J Lemmer, L Feller   +4 more
openaire   +1 more source

The Potential Effect of Oral Microbiota in the Prediction of Mucositis During Radiotherapy for Nasopharyngeal Carcinoma

EBioMedicine, 2017
Background: Oral mucositis is probably the most debilitating complication that can arise in treating a patient with head and neck cancer. Little is known about the impacts of oral microbiota on the initiation and progression of mucositis.
Xiao-Xia Zhu, Xiao-Jun Yang, Yi-Lan Chao, Hui-Min Zheng, Hua-Fang Sheng, Hai-Yue Liu, Yan He, Hong-Wei Zhou   +7 more
doaj   +1 more source