Results 91 to 100 of about 1,390,394 (194)

MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report

The Laryngoscope, EarlyView.
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio, Rachel D. Yoon, Steven Tomasi, Dana M. Thompson, Inbal Hazkani   +4 more
wiley   +1 more source

Therapeutic Interventions for Radiation‐Induced Fibrosis in Head and Neck Cancer Patients: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review and evaluate treatments for radiation‐induced fibrosis (RIF) following head and neck cancer (HNC) therapy. Data sources Medline, Embase.com, Web of Science, and Cochrane Library. Review Methods A systematic review was conducted on the management of HNC RIF using the Preferred Reporting Items for Systematic Reviews and Meta ...
Pooja D. Reddy, Purva Rumde, Vanessa Helou, Mary L. Klem, Matthew E. Spector, Marci L. Nilsen, Kevin J. Contrera   +6 more
wiley   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source

The influence of dental care associated with laser therapy on oral mucositis during allogeneic hematopoietic cell transplant: retrospective study

Einstein (São Paulo), 2011
Objective: To verify decrease in frequency and severity of oral mucositis in patients submitted to dental care and laser therapy during allogeneic hematopoietic cell transplant.
Fernanda de Paula Eduardo, Letícia Mello Bezinelli, Mariane Couto Estácio Orsi, Morgani Rodrigues, Martha Simões Ribeiro, Nelson Hamerschlak, Luciana Correa   +6 more
doaj   +2 more sources

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Effect of Oral Zinc Sulphate in Preventionof Radiation Induced OropharyngealMucositis During and After Radiotherapyin Patients with Head and Neck Cancers

Middle East Journal of Cancer, 2010
Introduction:Mucositis is a disturbing side effect of radiotherapy treatment forhead and neck cancer. To date, no effective modality for its prophylaxis and treatmenthas been found. We performed this study to evaluate the efficacy of oral zincsulphate in
Mohammad Mohammadianpanah, Shapour Omidvari, Mohammad Amin Mosleh-Shirazi, Mansour Ansari, Niloofar Ahmadloo, Hamid Nasrolahi, Ahmad Mosalaei, Amin Shafizad   +7 more
doaj  

Jasminum grandiflorum oral gel as an add-on to standard of care in radiation induced grade 2 oral mucositis - an open label pilot clinical trial

Journal of Ayurveda and Integrative Medicine
Background: Radiation-induced oral mucositis is one of the most critical dose-limiting toxicities associated with radiation therapy for oral cancer which can result in treatment interruption and compromise the quality of the life of cancer patients. Jati
A.R. Anuja, R. Anoop, Arun Mohanan, N.V. Ramesh   +3 more
doaj   +1 more source

Tratamento odontológico para pacientes submetidos à radioterapia em região de cabeça e pescoço: uma revisão de literatura [PDF]

, 2012
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.As neoplasias de cabeça e pescoço apresentam grande incidência no país. O prognóstico tardio dos carcinomas ainda é uma realidade, implicando terapias mais
Torres, Bruno Lucas Buzzi
core  

Facility Type Predicts Treatment Regimen for Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Treatment landscapes are changing for HPV+ oropharyngeal cancer (OPC) without compromising oncologic outcomes. We aim to analyze treatment trends of HPV+ OPC at academic (ACs) and nonacademic centers (NACs). Methods The National Cancer Database was queried, and multinomial logistic regression was used to predict treatment trends ...
Monica S. Trent, Kelsey Roman, Timothy I. Hsu, Yarah M. Haidar, Tjoson Tjoa   +4 more
wiley   +1 more source