Results 71 to 80 of about 1,390,394 (194)

Hepcidin promotes oral ulcer healing via amphiregulin production in rats

Journal of Dental Sciences
Background/purpose: Hepcidin is an antimicrobial peptide that regulates iron metabolism. Recently, hepcidin was reported to promote wound healing. However, the mechanism underlying hepcidin signaling in the oral mucosa remains unclear.
Naoto Taguchi, Suzuro Hitomi, Hitoshi Sato, Yoshinori Hayashi, Ikuko Shibuta, Koichi Iwata, Tatsuo Shirota, Masamichi Shinoda   +7 more
doaj   +1 more source

Oral mucositis induced by anticancer therapies [PDF]

, 2015
Oral mucositis induced by conventional cytotoxic cancer therapies is a common and significant clinical problem in oncology. Mucositis symptoms, which include severe pain, may lead to dose reductions and unplanned interruptions of chemotherapy and/or ...
Jan de Lange, de Lange, Jan, Fred R. Rozema, Barasch, Andrei, Rozema, F.R., Rozema, Fred R., Judith E. Raber-Durlacher, Barasch, A., de Lange, J., Judith A. E. M. Zecha, Raber-Durlacher, Judith E., Andrei Barasch, Zecha, J.A.E.M., Raber-Durlacher, J.E., Al-Ansari, S., Zecha, Judith A. E. M., Al-Ansari, Sali, Sali Al-Ansari   +17 more
core   +2 more sources

Stereotactic Body Radiotherapy (SBRT) of Previously Unirradiated Mucosal Head and Neck Squamous Cell Carcinoma (SCC)

Head &Neck, EarlyView.
ABSTRACT Purpose To evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) in previously untreated primary mucosal head and neck cancer (HNC) patients unfit for conventional radiation therapy. Materials and Methods Retrospective analysis of previously unirradiated primary SCC mucosal HNC patients treated with SBRT from 2011 to ...
Mohammed Aldohan, Irene Karam, Amir H. Safavi, Lee Chin, Liying Zhang, Ethan Gooanratne, Madette Galapin, Antoine Eskander, Kevin Higgins, Danny Enepekides, Ian Poon   +10 more
wiley   +1 more source

Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou, Pooja D. Reddy, Purva H. Rumde, Mary L. Klem, Sagar G. Kansara, Oldrich Virag, Yvonne M. Mowery, Nicole N. Scheff, Matthew E. Spector, Shaum Sridharan, Marci L. Nilsen, Kevin J. Contrera   +11 more
wiley   +1 more source

Twelve‐Month Outcomes of a Preventive Dysphagia Intervention in Patients With Head and Neck Cancer—A Randomized Study

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐associated dysphagia is common after radiotherapy for head and neck cancer and may occur early or years later. The effect of preventive exercises might be undermined by poor adherence. Aim To evaluate the effect of a simple preventive exercise protocol on swallowing function up to 12 months after radiotherapy.
Kerstin Petersson, Signe Rödseth Smith, Charlotte Johansson‐Malmeling, Caterina Finizia, Lisa Tuomi   +4 more
wiley   +1 more source

Head and Neck Lymph Node Metastases From Cancer of Unknown Primary: Outcomes From p16‐Guided Mucosal Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Background The AJCC 8th edition distinguishes p16‐positive oropharyngeal head and neck carcinoma of unknown primary (HNCUP) due to its superior prognosis. However, standardized radiation volume guidelines are lacking. This study evaluates the safety of p16‐guided mucosal volume reduction.
Philippe Harris, Dhiya‐Eddine Mabrouki, Felix‐Phuc Nguyen‐Tan, Edith Filion, Olivier Ballivy, Brian O'Sullivan, Apostolos Christopoulos, Tareck Ayad, Louis Guertin, Eric Bissada, Paul Tabet, Denis Soulières, Antoine Desilets, Alexandre Pellan Cheng, Robert Doucet, Laurent Létourneau‐Guillon, Houda Bahig   +16 more
wiley   +1 more source

Scales to graduate oral mucositis: What are the limitations?

, 2023
Oral mucositis is a common acute complication of a head and neck squamous cell carcinoma treatment. Multiple scales can be used to diagnose and grade this lesion, but they all have some limitation regarding this group of patients.
Karine Duarte Da Silva, Aline Maria Do Couto, Maria Cássia Ferreira De Aguiar, Adriele de Freitas Neiva Lessa, Daniela Pereira Meirelles   +4 more
core   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Perioperative Avelumab and Chemotherapy for Gastroesophageal Adenocarcinoma: Long‐Term Survival Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Long‐term survival data for patients with locally advanced gastro‐esophageal adenocarcinoma (GEA) treated with neoadjuvant chemoimmunotherapy are lacking. We describe the long‐term disease‐free survival (DFS) and overall survival (OS) outcomes of such patients treated with a novel neoadjuvant chemoimmunotherapy regimen, aDCF (avelumab with ...
Thierry Alcindor, James Tankel, Pierre‐Olivier Fiset, Mehrnoush Dehghani, Nicholas Bertos, Carmen Mueller, Jonathan Cools‐Lartigue, Sophie Camilleri‐Broet, Lorenzo Ferri   +8 more
wiley   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source