Results 61 to 70 of about 1,482,131 (288)

Oral Mucositis [PDF]

open access: yes, 2019
Oral mucositis is the inflammation of the mouth that affects hundreds of thousands cancer patients as a result of treatment, especially in patients with head and neck cancer. This paper will focus on the comprehension of the development of oral mucositis
Quijano, Lisseth
core   +1 more source

Effectiveness of cryotherapy in preventing oral mucositis in pediatric cancer patients in Jordan: a randomized controlled trial [PDF]

open access: yesChild Health Nursing Research
Purpose The study aimed to evaluate the effectiveness of cryotherapy in preventing oral mucositis in pediatric patients receiving chemotherapy. Methods An evidence-based practice project utilized a randomized control trial design with two groups ...
Khadeja Banat   +4 more
doaj   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit   +6 more
wiley   +1 more source

Treatment of oral mucositis due to chemotherapy [PDF]

open access: yes, 2016
Introduction: The management of oral mucositis is a challenge, due to its complex biological nature. Over the last 10 years, different strategies have been developed for the management of oral mucositis caused by chemotherapy in cancer patients. Material
Bagán Sebastián, José Vicente   +1 more
core  

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong   +10 more
wiley   +1 more source

Actual duration of patient-reported mucositis: Far longer than 2 to 4 weeks and may be avoidable altogether [PDF]

open access: yesKorean Journal of Clinical Oncology, 2016
The impression that oral mucositis is a brief 14–28 day-consequence of chemoradiation is misguided. Clinically significant patient-reported oral mucositis may last 46 to 102 days depending on the treatment schedule and the modality used.
Ricky Wayne McCullough
doaj   +1 more source

Next‐Generation CAR‐T Cell Therapy: From Modular Design to Clinical Expansion

open access: yesExploration, EarlyView.
Over the past decades, chimeric antigen receptor (CAR)‐T cell therapy has evolved from a linear engineering concept into a powerful yet constrained immunotherapy, limited by tumour microenvironment barriers, immune evasion, and manufacturing complexity.
Yuesong Bai   +5 more
wiley   +1 more source

Oral mucositis & oral health related quality of life in women undergoing chemotherapy for breast cancer in Karachi, Pakistan: A multicenter hospital based cross-sectional study.

open access: yesPLoS ONE
BackgroundOral mucositis is an inflammatory condition of oral cavity which is a common and serious side effect of cancer treatment. Severe oral mucositis compromises basic functions like eating and swallowing causing malnutrition also affecting overall ...
Asad Allana   +4 more
doaj   +1 more source

Depressive symptoms and oral mucositis in children with oncological diseases: a cross-sectional study [PDF]

open access: yesBrazilian Oral Research
The aim of this study was to investigate the correlation between depressive symptoms and the occurrence of oral mucositis in children with oncological diseases treated at a reference hospital.
Felipe Barreto LEMOS   +7 more
doaj   +1 more source

Stereotactic Body Radiotherapy (SBRT) of Previously Unirradiated Mucosal Head and Neck Squamous Cell Carcinoma (SCC)

open access: yesHead &Neck, EarlyView.
ABSTRACT Purpose To evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT) in previously untreated primary mucosal head and neck cancer (HNC) patients unfit for conventional radiation therapy. Materials and Methods Retrospective analysis of previously unirradiated primary SCC mucosal HNC patients treated with SBRT from 2011 to ...
Mohammed Aldohan   +10 more
wiley   +1 more source

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