Results 111 to 120 of about 1,482,131 (288)

Cytokeratin expression in initial oral mucositis of head and neck irradiated patients

, 2015
Objective. The aim of this work was to study cytokeratin (Ck) expression in initial radiation-induced oral mucositis. Study design. Eleven cases of initial radiomucositis of the buccal mucosa and 9 normal specimens were immunostained for Ck 1, 5, 6, 7, 8,
Pires, FR, Vargas, PA, de Almeida, OP, Kaminagakura, E, Bonan, PRF   +4 more
core   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

Can the oral microflora affect oral ulcerative mucositis?

, 2014
Purpose of review: Oral mucositis is one of the most prevalent toxicities after hematopoietic stem cell transplantation. Mucositis is initiated by the chemotherapy or radiotherapy preceding the transplantation. It is commonly accepted that microorganisms
Laheij, A.M.G.A.; id_orcid, Laheij, A.M.G.A., de Soet, J.J.   +2 more
core   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Daraxonrasib and Beyond: Pan‐RAS Inhibition, Resistance, and Next‐Generation Strategies

Cancer Science, EarlyView.
ABSTRACT RAS proteins have long been considered difficult therapeutic targets, but allele‐selective inhibitors established the clinical tractability of mutant RAS. Daraxonrasib (RMC‐6236), an oral pan‐RAS inhibitor, has now extended this concept by targeting multiple mutant and wild‐type RAS proteins.
Ryo Honda
wiley   +1 more source

Randomized Controlled Clinical Trial Comparing Screw‐Retained Monolithic Zirconia Implant Crowns on Standardized Titanium Base Versus Customized Titanium Abutments– 3‐Years Data

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To assess 3‐year interim results of implant‐supported monolithic zirconia single crowns on standardized titanium base vs. customized titanium abutments. Material and Methods Patients in need of posterior implant were recruited.
Jenni Hjerppe, Stephanie Wenk, Shunsuke Fukuba, Sven Mühlemann, Ronald E. Jung, Daniel S. Thoma   +5 more
wiley   +1 more source

Rebamipide gargle and benzydamine gargle in prevention and management of chemo-radiotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients (randomized clinical trial)

BMC Oral Health
Objectives This study aimed to evaluate the preventive and therapeutic effects of rebamipide gargle in comparison with benzydamine in head and neck cancer patients undergoing radiotherapy with or without chemotherapy.
Basma Elsaadany, Samah M. Anayb, Karim Mashhour, Mohammed Yossif, Fat’heya Zahran   +4 more
doaj   +1 more source

Clinical Outcomes of Fixed Dental Prostheses Supported by Teeth or Implants in the Posterior Region—A Long‐Term Retrospective Multicenter Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Background Few long‐term studies compare tooth‐ and implant‐supported fixed dental prostheses (FDPs) in the posterior region. Objectives To compare the 5‐ and 10‐year survival and complication outcomes of tooth‐ and implant‐supported FDPs and to assess patient‐reported effects. Material and Methods This retrospective multicenter clinical study
Zahra Athab Abduljabbar, Lars Hjalmarsson, Victoria Franke Stenport, Jir Barzangi, Anders Magnuson, Alf Eliasson   +5 more
wiley   +1 more source

An increase in Fusobacterium is associated with the severity of oral mucositis after radiotherapy

Scientific Reports
Radiotherapy is a common treatment for head and neck cancer but often causes oral mucositis, which reduces quality of life. Recent studies suggest that radiotherapy affects the oral microbiota, but whether it contributes to the severity of mucositis has ...
Atsushi Ue, Yukihisa Tamaki, Haruki Usuda, Unta Yamamori, Hiroshi Burioka, Natsuko Nagano, Masafumi Uno, Yoko Sonoyama, Takayuki Okamoto, Koichiro Wada   +9 more
doaj   +1 more source

Stratified Randomized Controlled Trial of ∅3.3 mm Versus ∅4.1 mm Hydrophilic Titanium‐Zirconium Implants Supporting Posterior Mandibular Fixed Prostheses in Hyperglycaemic Subjects

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective To compare ⌀3.3 mm and ⌀4.1 mm hydrophilic titanium‐zirconium implants supporting fixed dental prostheses (FDPs) in mandibular distal‐extension situations among participants with varying degrees of hyperglycaemia. Materials and Methods Participants were stratified according to HbA1c (5.8%–< 7.0% vs.
Supriya Ebenezer, Sreelakshmi Viswanath, Chitradevi Ramanathan, Alampalli V. Ramesh, Vinay V. Kumar   +4 more
wiley   +1 more source