Results 31 to 40 of about 369,599 (259)

Keratocystoma of palatal minor salivary glands: a case report

Journal of Oral Medicine and Oral Surgery
Keratocystoma is a rare benign tumor of the salivary glands. Initially described as a choristoma by Seifert et al. in 1999, the term “keratocystoma” was later proposed by Nagao et al. in 2001. The parotid gland is the most common site of occurrence. Only
Benaouf Souad, Kraloua Saadia, Larbi Meriem, El Amine Khebichat Moncef, Tabeti-Bentahar Cherifa Faiza   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Clinicopathologic Study of Oral Mucosa-Derived Hamartomas and Choristomas and Literature Review

International Journal of Dentistry
This study aimed to investigate the sociodemographic and clinicopathological data of oral soft tissue hamartomas and choristomas. A cross-sectional study was delineated to quantitatively analyze oral soft tissue hamartomas and choristomas cases diagnosed
Ianca Daniele Oliveira de Jesus, Anaíra Ribeiro Guedes Fonseca Costa, Débora de Oliveira Santos, Sérgio Vitorino Cardoso, Nayara Rúbio Diniz Del Nero, Adriano Mota Loyola, Paulo Rogério de Faria   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Diagnostic Value of Cytokeratin 17 during Oral Carcinogenesis: An Immunohistochemical Study

International Journal of Dentistry, 2021
Background. Little is known about the role of cytokeratin 17 (CK17) during oral carcinogenesis. CK17 expression in oral leukoplakia (OL), the most encountered oral potentially malignant disorders and oral squamous cell carcinoma (OSCC), remains very ...
Sirima Sanguansin, Theerachai Kosanwat, Rachai Juengsomjit, Sopee Poomsawat   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

TOPICAL CORTICOSTEROIDS IN ORAL PATHOLOGY [PDF]

Journal of IMAB, 2010
Topical corticosteroids have been commonly used over the last 50 years to treat various inflammatory mucosal conditions. The wide spectrum of potencies and bases allows these medications to be used effectively and safely under the care of an experienced ...
Adriana Krasteva, Assya Krasteva, Angelina Kisselova-Yaneva   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Histopathological Spectrum of a Calcifying Odontogenic Cyst With Uncommon Findings

Case Reports in Dentistry
Calcifying odontogenic cyst (COC) is an uncommon lesion accounting for less than 1% of all odontogenic cysts. This pathology commonly affects the anterior jaw and is prevalent in the second to third decades of life, with no sex predilection.
Saraswoti Khadka, Toniya Raut, Neetu Jain, Shashi Keshwar, Ashish Shrestha, Mehul Rajesh Jaisani, Khushbu Adhikari   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source