Results 141 to 150 of about 5,586,070 (250)
DISSOLUTION TEST FOR SOLID ORAL DOSAGE FORMS: MORE THAN JUST A TEST, AN ART
<p><span>Solid dosage forms, such as tablets and hard gelatine capsules have been on the market for a very long time. Despite the growth of biological molecules that are mainly given though parenteral routes (implying in a lot of cases, the ...
François-Xavier Lacasse +1 more
core +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.Chemical peptide synthesis allows the generation of structurally highly diverse compounds suited for ligand development, but current methods in parallel peptide synthesis limit the achievable library size to a few thousand. A strategy is presented based on combinatorial pairing of short peptides via disulfide linkage that enables the generation and ...
Anne Zarda +5 more
wiley +2 more sources
ION-EXCHANGE RESINS AS INGREDIENTS DRUG FORMULATIONS
Разработка и регистрация лекарственных средств, 2019 The article discusses the usage of ion-exchange resins (IOSs) as excipients and pharmaceutical substances. The main functions of IOSs as excipients are: taste masking, disintegration of tablets, stabilization of substances, modified release, etc.
N. B. Demina, D. D. Vorobyeva
doaj
Autonomous AI‐Driven Design for Skin Product Formulations
Advanced Intelligent Discovery, EarlyView.This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source
Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron
Angewandte Chemie, EarlyView.Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej +20 more
wiley +2 more sources
Assessment of Growth in Cardio‐Facio‐Cutaneous Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cardio‐facio‐cutaneous (CFC) syndrome is a rare, multiple congenital anomaly disorder in which individuals commonly experience faltering growth; however, systematic analysis of growth parameters in this disorder has not been performed. We recruited 69 participants with CFC through CFC International and collected data on assessing height ...
Kari Johnston +6 more
wiley +1 more source
The Application of Microwave Heating Methods in Pharmaceutical Formulations [PDF]
This study investigated the potential application of formulating pharmaceutical products using microwave heating methods alongside associated analytical investigations.
Bedford, Susan
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Native postbiotics and paraprobiotics derived from Lactobacillus and Bifidobacterium strains were administered to dextran sulfate sodium–treated C57BL/6 mice to evaluate their impact on kidney inflammation via the gut–kidney axis. Histological analysis and quantitative polymerase chain reaction of autophagy‐related genes (atg5, atg7, atg12, atg13 ...
Fatemeh Haririzadeh Jouriani +6 more
wiley +1 more source
Micellar Liquid Chromatography Determination of Edoxaban in Oral Solid Dosage Forms: Theoretical Aspects and Validation. [PDF]
ChemMedChemPeris-Vicente J +4 more
europepmc +1 more source