Results 31 to 40 of about 5,586,070 (250)

Drug release from matrix tablets: physiological parameters and the effect of food [PDF]

, 2014
Introduction: As dissolution plays an important and vital role in the drug-delivery process of oral solid dosage forms, it is, therefore, essential to critically evaluate the parameters that can affect this process. Areas covered: The consumption of
Ali Nokhodchi, Asare-Addo, Kofi, Kofi Asare-Addo, Nokhodchi, Ali, Ali Nokhodchi (4465915), Kofi Asare-Addo (4172488)   +5 more
core   +1 more source

Preparation of extemporaneous oral liquid in the hospital pharmacy

Brazilian Journal of Pharmaceutical Sciences, 2020
At the hospital, the pharmacist is constantly challenged to prepare extemporaneous solutions from tablets, capsules or drug powder for patients unable to swallow, such as pediatric, elderly and patients that use nasoenteric and nasogastric tubes.
Márcio Robert Mattos da Silva, Letícia Pereira Dysars, Elisabete Pereira dos Santos, Eduardo Ricci Júnior   +3 more
doaj   +1 more source

Solid oral dosage forms use in adults with neurological disorders and swallowing difficulties: A scoping review protocol

, 2021
Adults with neurological disorders commonly have dysphagia, which can affect swallowing solid oral dosage forms. This study aims to map the available published research about the interventions aiming at improving the effectiveness and safety of the use ...
Astrid Wiens, Rayza Assis de Andrade, Fernanda Tonin, Carolina Justus Buhrer Ferreira-Neto   +3 more
core   +1 more source

Ayurvedic Dosage Forms: Pressing Priorities and Challenges therein with Respect to Solid and Semisolid Oral Dosage Forms

Indian Journal of Ayurveda and Integrative Medicine KLEU
Continuous improvements in elevating traditional dosage forms to increase therapeutic efficacy, to enable patient-centric approaches, and to improve patient compliance are becoming more rational with advancements in technology and an advanced vision to ...
Sakshi Badyal, Poonam Dang, Puneet Dhawan, Himanshu Shekhar Tiwari   +3 more
doaj   +1 more source

Effect of Precirol ATO5 concentration and twin-screw melt granulation temperature on the physical properties of ascorbic acid granules

British Journal of Pharmacy, 2022
The pharmaceutical industry has a growing interest in continuous manufacturing, particularly for high-volume dosage forms such as solid oral tablets. This is driven by the obvious benefits such as small footprint, batch size flexibility, the relative ...
Valentyn Mohylyuk, David Jones, Shu Li, Yalin Ding, Gavin Patrick Andrews   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Natural Super-Disintegrant Agents Used in Various Oral Solid Dosage Forms [PDF]

, 2021
Super-disintegrating agents are one of the ingredients used in pharmaceutical solid dosage forms. These substances play a vital role in formulation design.  Natural super-disintegrants have gained more popularity due to their oral bioavailability ...
Krishna, CH. Vamsi, Sailaja, Nambaaru, Annammadevi, G.S., Iswariya, V.T.   +3 more
core   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Types of Attractive Dosage Forms for Primary School Students and Associated Factors in Baghdad/ Iraq

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
The lack of age-appropriate and child -friendly formulation of medication for children poses a major challenge to pediatric therapeutic practice, adherence, and health care delivery worldwide, however, formulation acceptability and preferences ...
Sura Zuhair Mahmood, Nora Zawar Yousif, Zeina Dawood Salman   +2 more
doaj   +1 more source