Results 41 to 50 of about 371,160 (303)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Oral Cavity–A Resilient Source for DNA Sampling

open access: yesThe Journal of Contemporary Dental Practice, 2022
Dear Editor, DNA is a double-stranded structure present inside the nucleus that carries all the inherited genomic information. Dental tissues are excellent sources of DNA as they show resistance to chemical and physical conditions.1 Dental enamel can withstand adverse conditions like humidity, microbial action, and high temperatures, thus preserving ...
Sujatha, Govindarajan   +3 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Oral sources for Documenting Socially Engaged Art: Applications and Theoretical Reflections from the Case Study of Contenuto Rimosso

open access: yespiano b
This study examines the possibility of incorporating participants' voices into the documentation practices of socially engaged art (SEA), using the interview as a tool to record and convey narratives that reflect the dialogical nature of these ...
Tanya Cecere
doaj   +1 more source

Tracing Islamic Sources in the Saraiki Folktales

open access: yesPakistan Journal of Islamic Research, 2021
Saraiki is one of the languages spoken by the people of Southern Punjab sine prehistoric times. Like all old languages of the world, this language has a long tradition of oral narratives especially the folktales which transferred by word of mouth from ...
Zahoor Hussain, Saiqa Imtiaz Asif
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Oral history: history overlooked by history

open access: yesCybrarians Journal, 2005
A study on oral history as one of the archival sources that received great attention from the International Council on Archives. The study begins by addressing the problems of oral history, then reviews its historical beginnings in Europe and different ...
Omnia Amer
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Acrolein—an α,ß-Unsaturated Aldehyde: A Review of Oral Cavity Exposure and Oral Pathology Effects

open access: yesRambam Maimonides Medical Journal, 2016
Acrolein is a highly reactive unsaturated aldehyde widely present in the environment, particularly as a product of tobacco smoke. Our previous studies indicated the adverse consequences of even short-term acrolein exposure and proposed a molecular ...
Dror Aizenbud   +3 more
doaj   +1 more source

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