Results 61 to 70 of about 1,275,299 (352)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Orapuh Journal, 2022 Oral health surveillance is an ongoing process involving the collection, analysis, and interpretation of data to produce information for the prevention and control of oral diseases.
Bemhemba Iba, Aondover Dogoh
doaj +2 more sources
Oral Method of History in the Investigation into the Resistance
Genocidas ir Rezistencija, 2008 Oral history is a qualitative method of historic documentation, applied to interview people in order to investigate certain events. Oral history started with an oral tradition, which sociologists began to investigate in the 19th century.
Lijana Pušinskytė
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Diabetic patients: their knowledge and perception of oral health [PDF]
Libyan Journal of Medicine, 2011 Objectives : The objectives of the study were to: 1 assess the knowledge and awareness of diabetic patients of their risk for systemic and oral diseases as complications associated with diabetes, 2 to assess their attitudes toward sustaining good oral ...
Aziza H. Eldarrat
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Las fuentes orales en la Enseñanza Superior. // Oral sources in Higher Education
Cabás, 2014 (ES) El interés por la historia presente ha llevado a considerar la historia oral como una herramienta que trasciende la investigación histórica para convertirse en una práctica de creación de patrimonio histórico. Planteamos la necesidad de utilizarlo
Guadalupe Trigueros Gordillo
doaj
Läti 20. sajandi ajaloo allikad: suulise ajaloo allikate ja arhiividokumentide dialoog [PDF]
Mäetagused, 2009 The article explicates the need to use oral history sources together with other types of sources in the study of the history of Latvia in the 20th century, to discover facts that have been kept concealed so far, and to render the view of the past in a ...
Irēna Saleniece
doaj
Debating whether Dinosaurs Should be "Cloned" from Ancient DNA to Promote Cooperative Learning in an Introductory Evolution Course [PDF]
, 2001 This interactive internet exercise engages students in cooperative library and web research on a controversial topic in science (and ethics), specifically the cloning of extinct forms of life.
Constance Soja, Deborah Huerta
core +1 more source