The Prognostic Role of CD8+ Tumor‐Infiltrating Lymphocyte Density in Head and Neck Mucosal Melanoma
Abstract Objective To explore the prognostic role of CD8+ tumor‐infiltrating lymphocytes (TIL) density in head and neck mucosal melanoma (HNMM) using an automated, quantitative, immunohistochemistry‐based methodology. Study Design Retrospective cohort study. Setting Single‐institution, tertiary care hospital.
Nicholas K. Fung +3 more
wiley +1 more source
Correction: Myeloid derived suppressor cells contribute to the malignant progression of oral squamous cell carcinoma. [PDF]
Pang X +11 more
europepmc +1 more source
Awake Blue Laser Excision and Balloon Dilation of Oropharyngeal Stenosis in High‐Risk Patients
Abstract Oropharyngeal stenosis is a rare condition that can develop following head and neck cancer treatment, leading to progressive dyspnea, dysphagia, and dysphonia. Patients with symptomatic dyspnea may benefit from endoscopic surgery. However, head and neck cancer survivors can have severe trismus, limited neck extension, and altered laryngeal ...
Abbey L. Landini +2 more
wiley +1 more source
Salivary telomere length in oral leukoplakia and oral squamous cell carcinoma: A preliminary case- control study. [PDF]
Chauhan A +5 more
europepmc +1 more source
The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski +7 more
wiley +1 more source
Safety and Efficacy of the Versius Surgical System in Transoral Robotic Surgery: A Prospective Study
Abstract Objective To evaluate the safety and feasibility of the Versius surgical robotic system for transoral robotic surgery in benign and malignant head and neck indications. Study Design Open‐label, prospective, single‐arm, phase II clinical trial. Setting Liverpool Head and Neck Centre, United Kingdom. Methods Between December 2023 and March 2025,
Jason C. Fleming +11 more
wiley +1 more source
Immunohistochemical evaluation of glutaminase-1 enzyme in oral squamous cell carcinoma. [PDF]
Chougule MS +5 more
europepmc +1 more source
Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review
Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally +7 more
wiley +1 more source
Transcriptome-based epigenetic screening identifies DNA hypermethylation signatures as prognostic biomarkers in oral squamous cell carcinoma. [PDF]
Han YK +5 more
europepmc +1 more source
Abstract Objective Dysphagia is a major toxicity of chemoradiation (CRT) for oropharyngeal squamous cell carcinoma (OPSCC). Elective upper‐neck irradiation (UNI), omitting the low neck, may reduce esophageal inlet muscle (EIM) dose and improve swallowing outcomes compared to elective whole‐neck irradiation (WNI).
Rex H. Lee +7 more
wiley +1 more source

