Results 51 to 60 of about 3,309,190 (263)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

‘Where are they now’? A survey of former oral surgery trainees

Introduction: This study aimed to gather demographic data from the oral surgery workforce who have experienced a formal training pathway, their current roles, commitments, competencies and how they believe oral surgery training could be improved. Methods:
Wilson, G, French, K, Gormley, M, Ali, S, Bailey, E, Stagnell, S   +5 more
core   +1 more source

Real‐Time Holographic Feedback via Mixed Reality Sensorized Laryngoscope Training System Enhances Pediatric Intubation Training

Advanced Robotics Research, EarlyView.
We proposed a Mixed Reality Sensorized Laryngoscope Training System to provide real‐time holographic torque feedback during pediatric endotracheal intubation simulation. Visualization formats are evaluated to reduce tracking error and visual demand.
Jiaqi Li, Ryman Hashem, Ningzhe Hou, Perla Maiolino, Louis Halamek, Liang He   +5 more
wiley   +1 more source

Resection margins in oral cancer surgery: Room for improvement

, 2016
The purpose of this review was to identify publications on resection margins in oral cancer surgery and compare these with the results from 2 Dutch academic medical centers. Eight publications were considered relevant for this study, reporting 30% to 65%
Molenaar, J, Ton P.M. Langeveld, Emilie A.C. Dronkers, Noordhoek Hegt, Vincent, Meeuwis, Cees, Jose A. Hardillo, Sewnaik, A., Jan Molenaar, Puppels, Gerwin, Robert J. Baatenburg de Jong, Hardillo, Jose, Dronkers, Emilie, V. Noordhoek Hegt, Baatenburg de Jong, R.J., Ivo ten Hove, Gerwin J. Puppels, Senada Koljenović, Langeveld, TPM, Hove, Ivo, Cees A. Meeuwis, Smits, Roeland, Tom C. Bakker Schut, Aniel Sewnaik, Roeland W.H. Smits, Koljenovic, Senada, Bakker Schut, Tom   +25 more
core   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

Oral midazolam sedation in third molar surgery

, 1987
A double-blind randomised study was designed to assess the value of oral midazolam in patients undergoing minor oral surgery. 30 young healthy Hong Kong Chinese with bilateral symmetrical impaction of lower third molars to be surgically removed in 2 ...
Rodrigo, MRC, Cheung, LK
core   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Breakthroughs in Oral and Maxillofacial Surgery

In the field of oral and maxillofacial surgery, continuous advances have ushered in a new era of innovation, profoundly influencing this branch of medicine [...
Amerigo Giudice, Alessandro Antonelli, Francesco Bennardo   +2 more
core   +1 more source

Effect of periapical surgery on oral health-related quality of life in the first postoperative week using the Dutch version of Oral Health Impact Profile-14

, 2021
Objective: To evaluate whether periapical surgery affects oral health-related quality of life (OHRQoL) within the first postoperative week. Study design: The primary outcomes in 133 patients (54 men, 79 women; mean age 50.8 years) undergoing periapical ...
Tuk, Jacco G., Lindeboom, Jerome A., van Wijk, Arjen J.   +2 more
core   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source