Results 51 to 60 of about 1,067,982 (301)

Effect of Membrane Exposure on Guided Bone Regeneration: A Systematic Review and Meta‐Analysis [PDF]

, 2018
Aims: This review aimed at investigating the effect of membrane exposure on guided bone regeneration (GBR) outcomes at peri-implant sites and edentulous ridges.
Allen, Annibali, Antoun, Arx, Arx, Arx, Assenza, Bahat, Bartee, Buser, Buser, Buser, Chao, Chiapasco, Chiapasco, Chiapasco, Chin, Cordaro, Cordaro, Cummings, Friedmann, Fu, Gher, Greenstein, Her, Hoffmann, Kfir, Lee, Liberati, Lim, Lindfors, Lizio, Lorenzoni, Lorenzoni, Louis, Lyford, Machtei, Mattout, Mellonig, Meloni, Merli, Misch, Miyamoto, Nowzari, Park, Park, Parodi, Proussaefs, Proussaefs, Proussaefs, Rakhmatia, Seibert, Sethi, Shea, Simion, Simion, Slim, Spray, Tal, Tarnow, Tawil, Torres, Uehara, Urban, Urban, Waasdorp, Wang, Wang, Wang, Wessing, Zitzmann   +70 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A case report of Parry Romberg Syndrome initially presenting as periodontitis [PDF]

, 2018
Parry Romberg Syndrome (PRS) is a rare disorder of progressive hemifacial atrophy, involving soft tissues, fat and occasionally bone. It can co-exist with presentations of Morphea.
Bramley, Duymaz, El-Kehdy, Fayad, Gorlin, Grippaudo, Lehman, Lewkonia, Mazzeo, Miller, Saraf, Stone, Sándor, Tollefson, Yu-Feng   +14 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Hendrickson Class II Palatal Fracture Following a Road Trauma Accident in a Pediatric Patient

Case Reports in Pediatrics
Pediatric palatal fractures are rare clinical presentations owing to the relative plasticity of their bones. We present a case of a 3-year-old pedestrian struck male patient presenting with a mid-sagittal palatal fracture which corresponds to a ...
Zilefac Brian Ngokwe, Ntep Ntep David Bienvenue, Nokam Kamdem Stephane, Noubissie Audrey Sandra, Bola Antoine Siafa   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Effects of Low-Level Laser Therapy on Osseous Defects Distal to Mandibular Second Molar after Extraction of Impacted Third Molar

Applied Bionics and Biomechanics, 2022
Objective. To evaluate the efficiency of low-level laser therapy on the distal osseous defects of the mandibular second molar (M2) after the adjacent impacted third molar (M3) extraction. Methods.
Ling-Yu Li, Jie Chen, Ming Yu, Yue-Ling Li, Gang Zhou   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Delayed Diagnosis and Multidisciplinary Management of a Compound Odontoma With Associated Dental Anomalies: A Rare Case Report

Case Reports in Dentistry
Hyperdontia is a developmental anomaly that can disrupt normal tooth eruption and occlusal harmony. Compound odontomas, although benign and often asymptomatic, may cause delayed eruption and other complications requiring surgical management.
Hussam Bajunaid, Yassin Hemoudi, Saeed Alqalaleef, Rakan Alshihri, Yousef Ezzat, Hisham Komo, Rayan Sharka, Hassan Abed   +7 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source