Results 151 to 160 of about 435,916 (297)

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Is this Judaism? The Question of the Consistency of Israeli Policy and Actions in Gaza with Jewish Thought and Ethics : Part 1: Formulating the problem and methodological and hermeneutic considerations. [PDF]

J Bioeth Inq
Komesaroff PA, Kenner JZ.
europepmc   +1 more source

The Global and the Local with a Focus on Africa [PDF]

Oral Tradition, 2003
Beverly Stoeltje
doaj  

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

<i>Fritillaria pallidiflora</i> Schrenk ex Fisch. & C.A.Mey. (Yi Beimu): Ethnopharmacology, Phytochemistry, Pharmacological Insights, and Future Prospects. [PDF]

Plants (Basel)
Aierken K, Li J, Waheed A.
europepmc   +1 more source

Classical Persian [PDF]

Oral Tradition, 2003
Olga Merck Davidson
doaj  

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

Exploration of hanging coffin customs and the bo people in China through comparative genomics. [PDF]

Nat Commun
Zhou H, Tao L, Zhao Y, He H, Shi H, Yu T, Guo Y, He Y, Liu H, Wu Y, Cao J, Kuang Z, Wu S, Lin F, Yang Y, Xiong L, Liu Y, Zhu K, Xu Y, Huang S, Yang X, Wang R, Wang B, Wang X, Lu WJ, Kutanan W, Shoocongdej R, Su B, Wang CC, Ji X, Zhang X.   +30 more
europepmc   +1 more source

Editor's Column [PDF]

Oral Tradition, 1992
John Miles Foley
doaj   +2 more sources

India's "Hundred Voices": Subaltern Oral Performance in Forster's A Passage to India [PDF]

Oral Tradition, 2002
John McBratney
doaj