Results 221 to 230 of about 127,439 (309)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey   +10 more
wiley   +1 more source

A novel oral vaccine delivery system for enhancing stability and immune protection: bacterium-like particle with functional coating. [PDF]

open access: yesFront Microbiol
De X   +11 more
europepmc   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

open access: yesAllergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche   +11 more
wiley   +1 more source

Assessing the clinical value of cervical biopsies in individuals with transformation zone type 3 at colposcopy: A cross‐sectional study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In transformation zone type 3, a systematic multiple biopsy protocol improved CIN2+ detection, particularly in high‐grade referrals, whereas yield remained limited in low‐grade referral cases. DSI‐assisted colposcopy did not increase biopsy sensitivity’.
Vibe Munk Bertelsen   +4 more
wiley   +1 more source

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