Results 51 to 60 of about 18,937 (242)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Temporal Patterning and “Degrees of Orality” in Occitan and French Oral Narrative
, 2023 International audienceThis article explores tense usage and tense-switching in the temporal structuring of Occitan and French oral narratives, drawing on theoretical frameworks in linguistics and sociolinguistics, as well as perspectives from ...
Carruthers, Janice +1 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Orality and the Ballad Tradition [PDF]
, 2012 Presenting a vexing problem for female aspirations to authorship, women and orality have been so close aligned as to be nearly indistinguishable,configured in a context which emphasises the national dimension to their creativity.
Gilbert, Suzanne
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Orality and Religion: The Ethno-Linguistic and Ritual Content of Ekajuk New Yam Festival [PDF]
, 2015 Orality is primordial transcends all races and permeates all facets of life from birth to maturity and death Each of these stages of human life and endeavor is prone to composition and delivery of Oral material as well as linguistic manipulation either
Francis M. Ganyi
core
Modelovanie sekundárnej orality
, 2016 Na sekundárnu oralitu môžeme nahliadať (minimálne) dvoma spôsobmi, čo dokazujú aj predložené modely, hoci oba prístupy sú vzájomne podmienené a pramenia jeden z druhého.
Fázik, Jakub
core +1 more source
The Body Onstage: orality and ethnoscenology
Revista Brasileira de Estudos da Presença, 2012 The analysis of the processes of human knowledge transmission, in general, reveal two ways: orality and writing. Traditionally, the scenic phenomenon is observed and analyzed as a variation of orality. With the creation and assertion of disciplines whose
Alexandra Gouvea Dumas
doaj
Technauriture as an Educational Tool in South Africa
Nordic Journal of African Studies, 2016 This article seeks to situate the importance of orality in southern African communities within the paradigm of Technauriture, that being the intersection of technology, auriture and literature and how it relates to imparting educational messages within ...
Russell H. Kaschula
doaj +1 more source