Results 61 to 70 of about 18,937 (242)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The End of Orality: Transmission of Gospel Tradition in the Second and Third Centuries

open access: yes, 2015
In a recent book Goodacre observes that in the early days of scholarship on the Gospel of Thomas "the majority view was that Thomas knew the Synoptic Gospels.
Charlesworth, Scott
core   +1 more source

The challenges of digitalization of civil justice: towards a flexible orality

open access: yesRevista Ítalo-Española de Derecho Procesal
Small claims proceedings are increasingly characterized by the prevalence of writing over orality. EU Regulation No. 861/2007 provides for proceedings that reduces but does not eliminate oral and direct contact between parties and judge.
Michele Angelo Lupoi
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Narratology and Orality in African Biblical Hermeneutics: Reading the story of Naboth's vineyard and Jehu's revolution in light of Intsomi yamaXhosa

open access: yesVerbum et Ecclesia, 2016
On the issue of methodology, oral literature has been decisive in the interpretation of the Hebrew Bible in Africa. For instance, Madipoane Masenya (ngwan a Mphahlele) convincingly employed the folktale of the Rabbit and the Lion in her interpretation ...
Ndikho Mtshiselwa
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Can we hear what they heard?: the effect of orality upon a markan reading-event [PDF]

open access: yes, 2002
This dissertation arises from recent investigations in the field of orality and the potential that it has for Markan studies. Chapter one identifies the epistemological divide which separates a contemporary reading experience from one situated in the ...
Smith, David F.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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