Optimized furosemide taste masked orally disintegrating tablets [PDF]
Optimized orally disintegrating tablets (ODTs) containing furosemide (FUR) were prepared by direct compression method. Two factors, three levels (32) full factorial design was used to optimize the effect of taste masking agent (Eudragit E100; X1) and ...
Mohamed Abbas Ibrahim +1 more
doaj +4 more sources
FORMULASI SEDIAAN ORALLY DISINTEGRATING TABLET ATENOLOL DENGAN SODIUM STARCH GLYCOLATE SEBAGAI SUPERDISINTEGRAN [PDF]
Atenolol, a competitive beta (1)-selective adrenergic antagonists, has been widely used in hypertension therapy. Administration of conventional tablets of atenolol has limitation due to patient compliance in geriatric patients. Formulation of atenolol as
Karina Citra Rani +2 more
doaj +5 more sources
Oral Bioavailability and Pharmacokinetics of Sildenafil Orally Disintegrating Tablets under Various Gastric pH Levels Following Administration of Omeprazole in Rats [PDF]
Sildenafil citrate, an oral drug used to treat erectile dysfunction, has low water solubility and oral bioavailability. The solubility is greatly influenced by the pH, changing from 37.25 mg/mL to 0.22 mg/mL with a change in pH from 1.2 to 8.0.
Chin-Yu Shih +4 more
doaj +2 more sources
Effect of food thickener and jelly wafer on the pharmacokinetics of levofloxacin orally disintegrating tablets [PDF]
This study was designed to determine the effects of a food thickener and deglutition aid jelly for oral administration, jelly wafer, on the pharmacokinetics of levofloxacin orally disintegrating tablets.
Takashi Tomita +9 more
doaj +2 more sources
Beyond Dysphagia in Parkinson’s Disease: 3D Printing of Orally Disintegrating Tablets (ODTs) for Optimized Treatment [PDF]
Parkinson’s disease (PD) is frequently complicated by dysphagia, undermining timely and reliable oral dopaminergic medication. Levodopa’s short half-life and delayed gastric emptying in advanced PD result in inconsistent absorption, delayed “ON” periods,
Ying-Ju Liao, Yao-Jen Liang
doaj +2 more sources
A Novel Lactose/MCC/L-HPC Triple-Based Co-Processed Excipients with Improved Tableting Performance Designed for Metoclopramide Orally Disintegrating Tablets [PDF]
New co-processed excipients comprising lactose (filler and sweetener), microcrystalline cellulose (MCC, filler), and low-substituted hydroxypropyl cellulose (L-HPC, disintegrant and binder) were developed via solvent evaporation for the preparation of ...
Xiaorong Dai +6 more
doaj +2 more sources
Development of muco-adhesive orally disintegrating tablets containing tamarind gum-coated tea powders for oral care [PDF]
The aim of this study was to design and evaluate muco-adhesive orally disintegrating tablets manufactured by microwave irradiation and containing polysaccharide.
Rika Kiniwa +5 more
doaj +2 more sources
Development of α-Cyclodextrin-Based Orally Disintegrating Tablets for 4-Phenylbutyrate [PDF]
Despite major improvements brought about by the introduction of taste-masked formulations of 4-phenylbutyrate (PB), poor compliance remains a significant drawback to treatment for some pediatric and dysphagic patients with urea cycle disorders (UCDs ...
Kindness L. Commey +9 more
doaj +2 more sources
Development of Orally Disintegrating Tablets of Standardized Rhodiola rosea Extract [PDF]
Background/Objectives: Rhodiola rosea L. (Crassulaceae), a perennial adaptogenic herb native to Northern Europe, Asia, and North America, is renowned for its therapeutic properties attributed to phenolic compounds including flavonoids, phenylethanoids ...
Oxana Brante +6 more
doaj +2 more sources
Recent Formulation Advances and Therapeutic Usefulness of Orally Disintegrating Tablets (ODTs) [PDF]
This review highlights the recent formulation advances (different methods of preparation involving various novel approaches) that have been advancing the use of ODT as a popular dosage form.
Maimoona Chinwala
doaj +2 more sources

