Results 61 to 70 of about 5,438 (215)
The effects of croscarmellose sodium concentration on the physicochemical characteristics of orodispersible tablets of atenolol [PDF]
, 2018 Hypertension is the most common cardiovascular diseases suffered by geriatric patients. Their physiological changes make the administration of conventional tablets less effective, especially regarding compliance.
Parfati, Nani, Rani, Karina Citra
core +2 more sources
Inhibition of the NLRP3 Inflammasome With MCC950 Improves Gut Health in Huntington's Disease Mice
Journal of Neurochemistry, Volume 170, Issue 4, April 2026.The NLRP3 inflammasome in HD (Huntington's disease) peripheral pathology (in gastrointestinal complications) is vastly unexplored. In this preclinical study, non‐invasive readouts of gut function assessment revealed that inhibiting NLRP3 inflammasome by chronic administration of MCC950 by oral route softened the faecal pellets, improved faecal output ...
Sujan Kumar Sarkar +10 more
wiley +1 more source
A Translation of Technology: MicroCoat™ to Sustained Release Orally Disintegrating Tablets
British Journal of Pharmacy, 2022 Orally disintegrating tablets (ODTs) comprising sustained release (SR) coated microparticles smaller than 250 µm provide an appealing dosage form for patients with dysphagia, offering a superior mouthfeel and highly convenient route of administration ...
Kavil Patel +3 more
doaj +1 more source
Characterising the disintegration properties of tablets in opaque media using texture analysis. [PDF]
, 2015 Tablet disintegration characterisation is used in pharmaceutical research, development, and quality control. Standard methods used to characterise tablet disintegration are often dependent on visual observation in measurement of disintegration times ...
Gerrard, Stephen E +5 more
core +3 more sources
Clinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.Abstract Daily oral cyclobenzaprine hydrochloride (HCl) has provided transient benefits in fibromyalgia, a chronic pain condition. To improve this effect, we evaluated sublingual formulations designed to drive transmucosal absorption. Two open‐label studies evaluated the pharmacokinetics (PK), tolerability, and relative bioavailability of sublingual ...
Bruce L Daugherty +4 more
wiley +1 more source
Optimizing outcomes in ADHD treatment: From clinical targets to novel delivery systems [PDF]
, 2016 Our knowledge and understanding of the underlying neurobiology and symptomatic expression of ADHD has advanced dramatically over the past decade. Associated with these advances has been a similar explosion of new treatment options to individualize ...
Anderson, Richard H +1 more
core +2 more sources
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Tablets showed > 79% steeper sourness growth than liquids by power law. Malic acid yielded steeper sourness growth than citric acid in most matrices and xylitol matrix yielded balanced perception with near‐unity sourness exponents. Time‐intensity parameters provide actionable targets for controlling sweetness‐sourness balance.
Chenchen Liu +4 more
wiley +1 more source
In vitro dissolution of proton-pump inhibitor products intended for paediatric and geriatric use in physiological bicarbonate buffer [PDF]
, 2015 Peer reviewedFinal Accepted ...
Liu, Fang, Shokrollahi, Honaz
core +1 more source
PEARL: Protein Eluting Alginate with Recombinant Lactobacilli
Small, Volume 22, Issue 16, 17 March 2026.Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri +7 more
wiley +1 more source
ORODISPERSIBLE TABLETS – A NOVEL APPROACH
Gomal Journal of Medical Sciences, 2017 Pharmaceutical technologists have developed a novel oral dosage forms known as orally disintegrating tablets or fast disintegrating tablets or mouth melting tablets or mouth dissolving tablets which disintegrate rapidly in saliva, usually in a matter of ...
Sattar Bakhsh Awan
doaj