Results 81 to 90 of about 5,438 (215)

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

Chewable Soft Gelatin Capsules: Design and Formulation Strategies for a Patient‐Preferred Dosage Alternative

Macromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.
Chewable softgels are a patient‐preferred alternative to conventional oral forms, offering pleasant taste, fast onset, and suitability for children or patients with swallowing difficulties. However, they present relevant challenges in their formulation: the shell must balance chewability, machinability, and stability, while the fill must mask the ...
Almudena Naharros‐Molinero, María Ángela Caballo‐González, Francisco Javier de la Mata, Sandra García‐Gallego   +3 more
wiley   +1 more source

Rapid acting fentanyl formulations in breakthrough pain in cancer: drug selection by means of the System of Objectified Judgement Analysis [PDF]

, 2017
Drug selection of rapid acting fentanyl formulations in the treatment of breakthrough pain in patients with cancer is performed by the System of Objectified Judgement Analysis method. All seven available formulations were included in the analysis.
Hanley, Jaquie, Janknegt, Robert, Knaggs, Roger, Schiere, Sjouke, Thronaes, Morten, van den Beuken, Marieke, Überall, Michael   +6 more
core   +2 more sources

Electrospun Composite Lavandula Angustifolia Mill. Extract/PVP Nanofibers

Macromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.
This study presents novel fast‐dissolving nanofibers electrospun from polyvinylpyrrolidone (PVP) loaded with crude lavender extract. The fibers form an amorphous solid dispersion, disintegrate within 1.5 s, and release 70%–90% of their payload within 5 min, significantly outperforming the pure extract.
Nan Yang, Gareth. R. Williams, Banaz Jalil, Olha Mykhailenko   +3 more
wiley   +1 more source

Fabrication of Orally Fast Disintegrating Wafer Tablets Containing Cannabis Extract Using Freeze Drying Method

Medical Cannabis and Cannabinoids
Introduction: The development of a novel dosage form for cannabis extract is necessary to improve drug delivery and to also enhance patient convenience.
Chaowalit Monton, Poj Kulvanich, Natawat Chankana, Jirapornchai Suksaeree, Thanapat Songsak   +4 more
doaj   +1 more source

Methodologies for Assessing the Acceptability of Oral Formulations among children and older adults: A Systematic Review [PDF]

, 2018
This is an open access article distributed under the terms and conditions of the Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/Acceptability of ...
Abu-Geras, Ahmed, Arnould, Babbitt, Bailey, Bayer, Beck, Bekele, Bellis, Bernabei, Bharmal, Brotherman, Bukstein, Carnaby-Mann, Catherine Tuleu, Ciavarella, Cloyd, Cohen, Cohen, Coleman, Cuzzolin, Czyzewski, Dagan, Davies, den Uyl, Diamond, Drumond, El Edelbi, Fabrice Ruiz, Fang Liu, Felipe Lopez, Fiona O’Brien, Fodil, Fukui-Soubou, Garvie, Geltman, Gore, Hansen, Holland, Jacobsen, Jagani, Jennifer Walsh, Kekitiinwa, Klingmann, Klingmann, Kluk, Koh, Kokki, Kozarewicz, Kraus, Kreeftmeijer-Vegter, Lai, Liu, Liu, Lloyd, Logrippo, Lottmann, MacDonald, Magalhaes, Marquis, Matza, McCrindle, McGillicuddy, Mekmullica, Meltzer, Mine Orlu, Mistry, Moniot-Ville, Mulla, Munck, Nahirya-Ntege, Nasrin, Nausieda, Ogutu, Overgaard, Patchell, Pein, Perkins, Phillips, Polaha, Quinzler, Ranmal, Rodd, Ruiz, Ruiz, Schiele, Schiele, Scolnik, Sebert, Sejal R. Ranmal, Sepponen, Shields, Sieb, Somogyi, Spomer, Steele, Stegemann, Stegemann, Strehle, Stubbs, Ternik, Thomson, Tuggey, Vallet, Valovirta, Van de Vijver, van Riet-Nales, Venables, Verrotti, Walsh, Weinberg, Winch, Zlotkin   +112 more
core   +3 more sources

Research Progress in the Treatment of Vaginitis With Bioactive Compounds: Targeting of Vaginal Microflora

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Mechanism diagram of the effect of herbal medicine on vaginitis. Herbal medicines mainly combat vaginitis by (A) inhibiting bacteria, (B) inhibiting fungi, (C) acting on the cilia of Trichomonas, (D) inhibiting virus replication, (E) repairing the mucosa, (F) enhancing immunity, and (G) maintaining the microecological balance.
Yongming Li, Huiyu Liu, Ruihan Li, Rong Li, Jiaqi Liu   +4 more
wiley   +1 more source

Management of erectile dysfunction with a novel orodispersible formulation of the PDE-5 inhibitor vardenafil [PDF]

, 2011
Erectile dysfunction (ED) is a medical condition which can affect men of all ages. As men live longer and the prevalence of cardiovascular disease and diabetes continue to increase, the problem of ED will become more prominent.
Cordina, Maria
core  

Effect of Spinacia oleracea on In Vitro Disintegration and Dissolution of Clopidogrel Bisulfate Tablets

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT Drug–food interactions may compromise therapeutic efficacy, particularly for life‐saving medications such as anticoagulants. Changes in gastric fluid properties, including pH modification and surface film formation, can alter drug dissolution and release. This study evaluated a potential interaction between clopidogrel and spinach and explored
Dana Sadaqa, Hani A. Naseef, Asma Radwan, Abdullah K. Rabba, Ramzi H. M. Muqedi   +4 more
wiley   +1 more source

Repurposing Oxfendazole for Onchocerciasis: Population Pharmacokinetics of a Tablet Formulation in Healthy African Adults

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Global efforts to eliminate onchocerciasis are hampered by the lack of a macrofilaricidal drug capable of killing adult parasites. Oxfendazole, a veterinary anthelminthic, exhibits macrofilaricidal activity and holds promise to shorten treatment durations.
Frauke Assmus, Ayorinde Adehin, Richard M. Hoglund, Gloria Nyaulingo, Hussein Mbarak, Said Jongo, Eveline Ackermann, Elisabeth Reus, Jennifer Keiser, Fabiana Barreira Da Silva Rocha, Sabine Specht, Ivan Scandale, Joel Tarning   +12 more
wiley   +1 more source