Results 141 to 150 of about 1,101,620 (303)

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Intramuscular orbital schwannoma: case report and review of the literature

Frontiers in Ophthalmology
Orbital schwannomas are benign tumors that arise from Schwann cells in the peripheral nerves in the orbit. They typically present after the second decade of life given their slow growth and rarely before then.
Hammam A. Alotaibi, Firas Madani, Rawan N. Althaqib, Hamad M. AlSulaiman   +3 more
doaj   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Nut graphs with a prescribed number of vertex and edge orbits [PDF]

arXiv
A nut graph is a nontrivial graph whose adjacency matrix has a one-dimensional null space spanned by a vector without zero entries. Recently, it was shown that a nut graph has more edge orbits than vertex orbits. It was also shown that for any even $r \ge 2$ and any $k \ge r + 1$, there exist infinitely many nut graphs with $r$ vertex orbits and $k ...
arxiv  

The Poynting-Robertson effect on meteor orbits

, 1950
Stanley P. Wyatt, Fred L. Whipple
openalex   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Training networks without wavefront label for pixel-based wavefront sensing

Frontiers in Physics
Traditional image-based wavefront sensing often faces challenges in efficiency and stagnation. Deep learning methods, when properly trained, offer superior robustness and performance.
Yuxuan Liu, Yuxuan Liu, Yuxuan Liu, Xiaoquan Bai, Xiaoquan Bai, Boqian Xu, Boqian Xu, Chunyue Zhang, Chunyue Zhang, Yan Gao, Yan Gao, Shuyan Xu, Shuyan Xu, Guohao Ju, Guohao Ju   +14 more
doaj   +1 more source

Violation of local reciprocity in charge-orbital interconversion [PDF]

arXiv
We demonstrate a violation of local reciprocity in the interconversion between charge and orbital currents. By investigating orbital torque and orbital pumping in W/Ni bilayers, we show that the charge-orbital interconversion in the bulk of the W layer exhibits opposite signs in the direct and inverse processes -- the direct and inverse orbital Hall ...
arxiv  

On orbits of homeomorphisms [PDF]

, 1958
Shinichi Kinoshita
openalex   +1 more source