Protein kinase FAM20C—when subcellular localization matters
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Solitary eyelid neurofibroma presenting as tarsal cyst: Report of a case and review of literature
Purpose: To report a rare case of solitary eyelid neurofiboma presenting as tarsal cyst. Observation: A 64 year old male, presented with a painless, non progressive swelling in the right upper eye lid.
Nisar Sonam Poonam +3 more
doaj +1 more source
Orbital Dependence of Galaxy Properties in Satellite Systems of Galaxies
We study the dependence of satellite galaxy properties on the distance to the host galaxy and the orbital motion using the SDSS data.
Abazajian +34 more
core +1 more source
The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation
Background Therapeutic decisions in atrial fibrillation (AF) are often influenced by assessment of bleeding risk. However, existing bleeding risk scores have limitations.
Emily C. O'Brien +12 more
semanticscholar +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Current-induced torques in textured Rashba ferromagnets
In systems with small spin-orbit coupling, current-induced torques on the magnetization require inhomogeneous magnetization textures. For large spin-orbit coupling, such torques exist even without gradients in the magnetization direction.
E. I. Rashba +2 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Carotid cavernous fistula masquerading as delayed suprachoroidal hemorrhage after trabeculectomy
Objective: Carotid cavernous fistulae (CCFs) are abnormal communications between the cavernous sinus and the carotid arterial system. Based on the etiology, CCFs can be traumatic, spontaneous and rarely iatrogenic.
Jain, Mukesh +3 more
doaj +1 more source
Zitterbewegung of a heavy hole in presence of spin-orbit interactions
We study the $zitterbewegung$ of a heavy hole in presence of both cubic Rashba and cubic Dresselhaus spin-orbit interactions. On contrary to the electronic case, $zitterbewegung$ does not vanish for equal strength of Rashba and Dresselhaus spin-orbit ...
Biswas, Tutul +2 more
core +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source

