Results 31 to 40 of about 106,838 (268)

Orbital tuberculosis presenting as vision loss and headache: early management is paramount

Journal of Ophthalmic Inflammation and Infection
Orbital tuberculosis is a rare form of extra pulmonary TB and may arise either by hematogenous route or spread directly from the paranasal sinus. We herein report two cases of orbital TB with a vision threatening complication.
Sandeep Pal, Narendra Patidar, Gunjan Tomar, Himanshu Gaikwad   +3 more
doaj   +1 more source

Earth Observation Mission of a 6U CubeSat with a 5-Meter Resolution for Wildfire Image Classification Using Convolution Neural Network Approach

Remote Sensing, 2022
The KITSUNE satellite is a 6-unit CubeSat platform with the main mission of 5-m-class Earth observation in low Earth orbit (LEO), and the payload is developed with a 31.4 MP commercial off-the-shelf sensor, customized optics, and a camera controller ...
Muhammad Hasif bin Azami, Necmi Cihan Orger, Victor Hugo Schulz, Takashi Oshiro, Mengu Cho   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Research on Actuator Control System Based on Improved MPC

Actuators
To improve the control accuracy and interference resistance of actuator control systems in complex environments, a complete actuator control system solution has been designed.
Qingjian Zhao, Qinghai Zhang, Shuang Zhao, Xiaoqian Zhang, Shilei Lu, Yang Guo, Liqiang Song, Zhengxu Zhao   +7 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

AI-Driven Analysis of Wrist-Worn Sensor Data for Monitoring Individual Treatment Response and Optimizing Levodopa Dosing in Parkinson’s Disease

Sensors
Parkinson’s Disease is a progressive neurodegenerative disorder marked by motor fluctuations in later disease stages that complicate treatment with levodopa.
Mathias Sander, Moritz R. Messner, Sina K. Knapp, Franz M. J. Pfister, Urban M. Fietzek   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Poorly differentiated sebaceous carcinoma of the lacrimal sac in a young adult: A case report

SAGE Open Medical Case Reports
Lacrimal sac and nasolacrimal duct tumors are extremely rare, and most of them are malignant tumors, which are often misdiagnosed as chronic dacryocystitis. We herein report a rare case of a 29-year-old female, presented with a history of watering in the
Sandeep Pal, Narendra Patidar, Ashik R, Poonam Arora Agrawal, Dev Kumar Tekam   +4 more
doaj   +1 more source