Results 51 to 60 of about 220,364 (241)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Assessment of numerical differentiation methods for kinematic orbit solution of the GRACE mission [PDF]

open access: yes, 2013
textThe historical method of precise orbit determination is a dynamic approach. However, with the improvement of GPS tracking data and associated tracking networks, two newer methods have been developed: reduced-dynamic and kinematic.
Krishnan, Sandeep Kalyanapuram
core  

Orbital varices and orbital wall defects [PDF]

open access: yesBritish Journal of Ophthalmology, 2004
Orbital varices are a vascular hamartoma typified by a plexus of low pressure, low flow, thin walled and distensible vessels that intermingle with the normal orbital vessels.1–4 If freely communicating with the orbital circulation, engorgement of varices can occur by increasing venous pressure through the Valsalva manoeuvre,5 bending posture,6 coughing
N, Islam, K, Mireskandari, G E, Rose
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

First In-orbit Experience of TerraSAR-X Flight Dynamics Operations [PDF]

open access: yes, 2007
TerraSAR-X is an advanced synthetic aperture radar satellite system for scientific and commercial applications that is realized in a public-private partnership between the German Aerospace Center (DLR) and the Astrium GmbH.
Kiehling, Reinhard   +11 more
core  

AI-Driven Analysis of Wrist-Worn Sensor Data for Monitoring Individual Treatment Response and Optimizing Levodopa Dosing in Parkinson’s Disease

open access: yesSensors
Parkinson’s Disease is a progressive neurodegenerative disorder marked by motor fluctuations in later disease stages that complicate treatment with levodopa.
Mathias Sander   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Visual Navigation For On-Orbit Servicing Missions [PDF]

open access: yes, 2013
Increasing complexity and costs of satellite missions promote the idea of looking for opportunities to extend the operational lifetime or to improve the performance of a satellite instead of simply replacing it by a new one.
Tzschichholz, Tristan   +2 more
core  

Observation of two distinct cold, dense ion populations at geosynchronous orbit: Local time asymmetry, solar wind dependence and origin [PDF]

open access: yes, 2006
International audienceWe report on the observation of two distinct cold (TiNi>2 cm?3) ion populations at geosynchronous orbit. A statistical study was performed on measurements from the geosynchronous Los Alamos plasma instruments, for the period 1990 ...
Aasnes, A.   +17 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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