Results 71 to 80 of about 220,364 (241)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Mature teratoma presenting as orbital cellulitis in a 5-month-old baby

open access: yesAnnals of Saudi Medicine, 2013
We have presented an interesting case of an unexpected orbital tumor in a 5-month-old female healthy baby who presented initially with a 1-week history of acute left proptosis, swollen eyelid, conjunctival chemosis and exposure keratopathy.
Hind Manaa Alkatan   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Enhanced YOLOv8-based method for space debris detection using cross-scale feature fusion

open access: yesDiscover Applied Sciences
Optical observations play a crucial role in monitoring space debris, and long exposure large field-of-view telescopes exhibit robust detection capabilities for identifying space debris.
Yang Guo   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

STar-DETR: A Lightweight Real-Time Detection Transformer for Space Targets in Optical Sensor Systems

open access: yesSensors
Optical sensor systems are essential for space target detection. However, previous studies have prioritized detection accuracy over model efficiency, limiting their deployment on resource-constrained sensors.
Yao Xiao   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Orbit Precision Analysis of Small Man-Made Space Objects in LEO Based on Radar Tracking Measurements [PDF]

open access: yes, 2012
The German Space Operations Center (GSOC) performs collision avoidance for 11 LEO and 2 GEO satellites. Risk detection and maneuver decisions strongly depend on the computed probability of collision that is driven by the anticipated orbit precision of ...
Letsch, Klemens   +6 more
core  

Enhancing Bidirectional Modbus TCP ↔ RTU Gateway Performance: A UDP Mechanism and Markov Chain Approach

open access: yesSensors
In the Industrial Internet of Things (IIoT) field, the diversity of devices and protocols leads to interconnection challenges. Conventional Modbus Transmission Control Protocol (TCP) to Remote Terminal Unit (RTU) gateways suffer from high overhead and ...
Shuang Zhao   +7 more
doaj   +1 more source

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