Results 41 to 50 of about 329,030 (268)

Ptosis, ophthalmoplegia and corneal endothelial disease – ocular manifestations of mitochondrial disease

American Journal of Ophthalmology Case Reports, 2021
Purpose: To describe two patients with bilateral ptosis, ophthalmoplegia, cataracts and corneal endothelial disease requiring corneal transplantation.
Elizabeth M. McElnea, Zelda S. Pick, Aoife C. Smyth, Louis J. Stevenson, Penny A. McKelvie, Michael S. Loughnan, Alan A. McNab   +6 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Enhancing Bidirectional Modbus TCP ↔ RTU Gateway Performance: A UDP Mechanism and Markov Chain Approach

Sensors
In the Industrial Internet of Things (IIoT) field, the diversity of devices and protocols leads to interconnection challenges. Conventional Modbus Transmission Control Protocol (TCP) to Remote Terminal Unit (RTU) gateways suffer from high overhead and ...
Shuang Zhao, Qinghai Zhang, Qingjian Zhao, Xiaoqian Zhang, Yang Guo, Shilei Lu, Liqiang Song, Zhengxu Zhao   +7 more
doaj   +1 more source

Dynamic Modelling and Continuous Trajectory Tracking Control of Space Robots Based on Lie Group SE(3)

International Journal of Aerospace Engineering, 2023
For space robots, it is difficult to track continuous time-varying manifolds on SE(3) by using traditional closed-loop control strategies, which are designed to track the position and the attitude separately.
Yong Wang, Kejie Gong, Yurui Duan, Boyong He, Hong Ma   +4 more
doaj   +1 more source

Evidence of Magnon-Mediated Orbital Magnetism in a Quasi-2D Topological Magnon Insulator [PDF]

, 2022
Laith Alahmed, Xiaoqian Zhang, Jiajia Wen, Yuzan Xiong, Yi Li, Lichuan Zhang, Fabian R. Lux, Frank Freimuth, Muntasir Mahdi, Yuriy Mokrousov, V. Novosad, W. K. Kwok, Dapeng Yu, Wei Zhang, Young S. Lee, Peng Li   +15 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Chirality-enabled topological phase transitions in parity-time symmetric systems

New Journal of Physics
Photonic spin Hall effect (PSHE) in chiral PT-symmetric systems exhibits many exotic features, but the underlying physical mechanism has not been well elucidated.
Yong Cao, Lijuan Sheng, Qiang Zhou, Rong Wang, Zhenkuan Chen, Xiaohui Ling   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source