Results 61 to 70 of about 3,365,879 (300)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development Strategy of Orbit Determination System for Korea’s Lunar Mission: Lessons from ESA, JAXA, ISRO and CNSA’s Experiences [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2014
In this paper, a brief but essential development strategy for the lunar orbit determination system is discussed to prepare for the future Korea’s lunar missions.
Young-Joo Song, Sang-il Ahn, Eun-Sup Sim
doaj   +1 more source

Assessment of Swarm Kinematic Orbit Determination Using Two Different Double-Difference Methods

open access: yesRemote Sensing, 2023
The Swarm mission aims to study the principle and change regularities of the Earth’s magnetic field. Precise orbit determination is essential to the successful implementation of the mission and relevant scientific research.
Rui Zhang   +5 more
doaj   +1 more source

Orbit Determination with the Keplerian Integrals

open access: yes, 2022
We review two initial orbit determination methods for too short arcs (TSAs) of optical observations of a solar system body. These methods employ the conservation laws of Kepler's problem, and allow to attempt the linkage of TSAs referring to quite far epochs, differing by even more than one orbital period of the observed object.
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

PPP-based Swarm kinematic orbit determination [PDF]

open access: yesAnnales Geophysicae, 2018
The Swarm mission of the European Space Agency (ESA) offers excellent opportunities to study the ionosphere and to provide temporal gravity field information for the gap between the Gravity Recovery and Climate Experiment (GRACE) and its follow-on ...
L. Ren, S. Schön
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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