Results 91 to 100 of about 163,907 (339)
Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice. [PDF]
, 2019 Approximately 15-40% of all cancers develop metastases in the central nervous system (CNS), yet few therapeutic options exist to treat them. Cancer therapies based on monoclonal antibodies are widely successful, yet have limited efficacy against CNS ...
Chen, Irvin SY +17 more
core
, 2020 A new stable phosphorus ylide (p-tolyl)(3)P = CHCOC6H4(p-CN) (Y) was synthesized and a series of novel complexes based on metalated phosphorus ylides were prepared through the reaction of (p-tolyl)(3)P = CHCOC6H4(p-CN) with mercury(II) halides, AgNO3 and
Bayat, Mehdi +5 more
core +1 more source
Advanced Functional Materials, EarlyView.PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source
Functionalization and Characterization of Magnetic Nanoparticles for the Detection of Ferritin Accumulation in Alzheimer's Disease [PDF]
, 2018 Early diagnosis in Alzheimer's disease (AD), prior to the appearance of marked clinical symptoms, is critical to prevent irreversible neuronal damage and neural malfunction that lead to dementia and death.
Cussó, Lorena +4 more
core +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Clinicopathological and genetic analysis of orbital solitary fibrous tumors
BMC OphthalmologyPurpose To investigate the clinicopathological and genetic characteristics of patients with orbital solitary fibrous tumor (SFT) for clinical reference. Methods This single-center retrospective case-series study assessed clinical manifestations, imaging ...
Qing Wang +8 more
doaj +1 more source
Malignant Melanoma of Nose and Paranasal Sinuses: 2 Case Reports [PDF]
, 2010 Malignant melanoma is one of the rare and highly aggressive diseases of the sinonasal cavity. High index of suspicion is required for diagnosis as the patient usually presents with non specific signs and symptoms.
Bhagat, S +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain +5 more
wiley +1 more source
Orbital imaging – Scanning a patient, reading a disease
, 2021 Santosh G Honavar
openalex +1 more source
Orbital Rosai-Dorfman disease initially diagnosed as IgG4-related disease: a case report [PDF]
, 2020 Nishanth S. Iyengar +12 more
openalex +1 more source