Results 31 to 40 of about 66,246 (264)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Investigation using single point incremental forming (SPIF) to fabricate patient-specific, titanium orbital floor implants [PDF]

MATEC Web of Conferences
The floor of the human orbit is composed of thin bone that is prone to traumatic fracture. This leads to a loss of support for the eye, which can cause vision changes. Therefore, fractures may need surgical reconstruction using a thin, sheet-like implant.
Mamros Elizabeth M., Blaha Lauren E., Kauffman Christian A.   +2 more
doaj   +1 more source

Ontology‐Aligned Structuring and Reuse of Multimodal Materials Data and Workflows Toward Automatic Reproduction

Advanced Engineering Materials, EarlyView.
Reproduction of stacking fault energy calculations from literature with a semi‐automated large language model‐assisted extraction procedure: extraction of simulation protocol, atomistic structures, computational parameters, and reported results, ontology alignment, knowledge graph construction and, finally, recomputation forvalidation.
Sepideh Baghaee Ravari, Abril Azocar Guzman, Sarath Menon, Stefan Sandfeld, Tilmann Hickel, Markus Stricker   +5 more
wiley   +1 more source

Geometry of Wave-Formed Orbital Ripples in Coarse Sand [PDF]

Journal of Marine Science and Engineering, 2015
Using new large-scale wave-flume experiments we examine the cross-section and planform geometry of wave-formed ripples in coarse sand (median grain size D50 = 430 μm) under high-energy shoaling and plunging random waves. We find that the ripples remain
Gerben Ruessink, Joost Brinkkemper, Maarten Kleinhans   +2 more
openaire   +4 more sources

Electrochemical Behavior of Flame‐Sprayed Sc‐Doped AlCoCrFeMo High‐Entropy Alloy Coatings in 3.5% Sodium Chloride Solution

Advanced Engineering Materials, EarlyView.
Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar, Akash Vyas, Mohammad Aatif Qazi, Nashit Jalal, Maria Ophelia Jarligo, Mostafa Yakout, Jing Liu, André McDonald   +7 more
wiley   +1 more source

Crystal structure, DFT and MEP study of (E)-2-{[(3-chlorophenyl)imino]methyl}-6-methylphenol

Acta Crystallographica Section E: Crystallographic Communications, 2020
In the crystal structure of the title compound, C14H12ClNO, the molecules are linked through C—H...O hydrogen bonds and C—H...π interactions, forming chains parallel to the [010] direction.
Hanife Saraçoğlu, Onur Erman Doğan, Tuğgan Ağar, Necmi Dege, Turganbay S. Iskenderov   +4 more
doaj   +1 more source

The Effect of Thickness on Strength of Single Lap Orbital Riveted Aluminum/Composite Joints Used in Marine Environments

Metals, 2022
In an innovative vision of manufacturing, orbital riveting is a joining technique characterized by high efficiency, energy saving, low costs and low noise.
Guido Di Bella, Tiziana Alderucci, Federica Favaloro, Chiara Borsellino   +3 more
doaj   +1 more source

Values of harmonic weak Maass forms on Hecke orbits [PDF]

Journal of Mathematical Analysis and Applications, 2019
Let $q:=e^{2 πiz}$, where $z \in \mathbb{H}$. For an even integer $k$, let $f(z):=q^h\prod_{m=1}^{\infty}(1-q^m)^{c(m)}$ be a meromorphic modular form of weight $k$ on $Γ_0(N)$. For a positive integer $m$, let $T_m$ be the $m$th Hecke operator and $D$ be a divisor of a modular curve with level $N$.
Choi, Dohoon, Lee, Min, Lim, Subong
openaire   +3 more sources