Results 121 to 130 of about 38,213 (313)

Research on the clinical and pathological characteristics of primary orbital neoplastic lesions with communication

BMC Ophthalmology
Objective To comprehensively summarize the clinical and pathological characteristics of primary orbital neoplastic lesions with communication, thereby providing a solid basis for the diagnosis and treatment of such conditions.
Lian Wang, Jing Zhang, Shuo Zhang, Bin Li, Bentao Yang, Hongjuan Liu, Chunli Chen, Qiong Wu, Libin Jiang   +8 more
doaj   +1 more source

Rare Orbital Metastasis of Carcinoid Tumor Despite Long-Term Somatostatin Therapy: A Case Report

Reports
Background and Clinical Significance: Carcinoid tumors are rare, slow-growing neuroendocrine cell neoplasms that typically affect the gastrointestinal tract.
Hritika Hosalkar, Leo Meller, Nahia Dib El Jalbout, Marissa K. Shoji, Sally L. Baxter, Don O. Kikkawa   +5 more
doaj   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Closure of perforations of the septum including a single- session method for large defects [PDF]

, 1983
Berghaus, Alexander, Meyer, R.
core   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

Advanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou, Ke Li, Xuelan Li, Lei Yi, Zhengxiang Wang, Huan Ding, Sheng Wu, Feiyu Liu, Yuan Li, Rui Cheng, Jianliang Shen   +10 more
wiley   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Sinonasal Teratocarcinosarcoma Involving Orbital and Intracranial Extension: A Rare Case Report

Ear, Nose & Throat Journal
Sinonasal teratocarcinosarcoma (SNTCS) is one of the rarest and most highly invasive malignant neoplasms often found in the nasal cavity and paranasal sinuses. SNTCS is often misdiagnosed because of its morphological heterogeneity.
Tao Zhou, Yuan Tian, Zhipeng Zhu, Jianxin Yue, Qing Cheng, Xun Niu, Yue Zhou, Jun Fan, Liuqing Zhou, Haiying Sun   +9 more
doaj   +1 more source

Designing a training tool for imaging mental models [PDF]

The training process can be conceptualized as the student acquiring an evolutionary sequence of classification-problem solving mental models. For example a physician learns (1) classification systems for patient symptoms, diagnostic procedures, diseases,
Dede, Christopher J., Jayaram, Geetha
core   +1 more source

Endoscopic ultrasonic curette-assisted removal of frontal osteomas [PDF]

, 2014
Indications for endoscopic resection of fronto-ethmoidal osteomas have been progressively expanded thanks to optimization of surgical exposure and the development of dedicated instruments.
Bolzoni Villaret, A, Esposito, I, Nicolai, P, Schreiber, A   +3 more
core   +1 more source