Results 161 to 170 of about 32,740 (261)

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1

open access: yesChemistry – A European Journal, EarlyView.
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang   +5 more
wiley   +1 more source

Effects of Biotin on a Fluorescein‐Based Photosensitizer Revealed by Multiscale Computational Modeling

open access: yesChemistry – A European Journal, EarlyView.
Biotinylation of a fluorescein‐based photosensitizer enhances its performance in PDT through a synergistic dual action. In addition to Type II singlet oxygen generation common to both dyes, the biotinylated system induces stronger membrane perturbation and higher local accumulation in lipid membranes, associated with increased water permeability and ...
Valeria Butera   +4 more
wiley   +1 more source

Synthesis of Tris(indol‐3‐yl)methanes From Indoles, CO2, and Dimethylphenylsilane With BPh3: Two‐Step Construction of π‐Conjugated Systems

open access: yesChemistry – A European Journal, EarlyView.
Tris(indol‐3‐yl)methanes were synthesized from indoles, CO2, and PhMe2SiH in the presence of BPh3 in acetonitrile at 50°C. One product, tris(4‐bromo‐1‐methylindol‐3‐yl)methane, underwent a palladium‐catalyzed cascade reaction for the formation of a novel polycyclic heteroaromatic compound, where the methine C(sp3) atom originating from CO2 was ...
Sha Li   +5 more
wiley   +1 more source

Ocular Adnexal Lymphoma: An Ophthalmologist's Perspective from a Single-center Experience. [PDF]

open access: yesCancer Diagn Progn
Pojda-Wilczek D   +4 more
europepmc   +1 more source

Experimental methods in chemical engineering: Magnetometry

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Magnetometry is a non‐invasive technique to characterize the behaviour of magnetic materials of which the most common contain Fe, Co, and Ni. Vibrating sample magnetometers (VSMs) vibrate samples at a fixed frequency in a static, homogeneous magnetic field to induce a voltage in pick up coils according to Faraday's law of induction.
Michael Claeys   +3 more
wiley   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

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