Results 171 to 180 of about 32,570 (261)

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, EarlyView.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Histopathological spectrum of ocular masses in a tertiary eye center in Northern China: a 12-year retrospective analysis. [PDF]

Front Med (Lausanne)
Ren S, Wang P, Li B, Zhang C, Zhang M.
europepmc   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

International Journal of Cancer, EarlyView.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley, Liesbet J. Van Eycken, Meredith E. Giuliani, Brian A. Rous, Shao Hui Huang, Hisao Asamura, Mary K. Gospodarowicz, Anne W. Lee, Brian O'Sullivan   +8 more
wiley   +1 more source

Orbital Myiasis Secondary to Neglected Maxillary Sinus Squamous Cell Carcinoma in an 85-Year-Old Woman: A Case Report. [PDF]

Int Med Case Rep J
Trung NL, Ngan ND, Mai PT, Manh NT.
europepmc   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

Multifocal Rosai Dorfman disease and simultaneous endometrioid ovarian cancer: a case report. [PDF]

J Med Case Rep
Graf N, Halbsguth T, Becker S, Tahmasbi Rad M.   +3 more
europepmc   +1 more source

Evaluation of Panoramic Acquisition Errors by Predoctoral Dental Students

Journal of Dental Education, EarlyView.
Abstract Objectives Panoramic radiography is commonly used in the management of dental‐alveolar pathology. Novice clinicians are prone to technical errors that diminish the diagnostic quality of radiographs. The objective of this study was to analyze technical errors made during panoramic exposures by third‐year (D3) dental students in order to enhance
Zachary B. Featherstone, Xiaoxi Cui, Wenjian Zhang   +2 more
wiley   +1 more source

Ocular Manifestations Associated with Hematologic Malignancies: Mechanisms, Diagnosis, and Management. [PDF]

Med Sci (Basel)
Xiao Y, Zou Y, Yang M, Zhang J, Ohno-Matsui K, Kamoi K.   +5 more
europepmc   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

Journal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang, Nan Song, Huanhuan Qiao, Si Sun   +3 more
wiley   +1 more source

A Scoping Review of Artificial Intelligence in Ocular Oncology. [PDF]

Cancers (Basel)
Vempuluru VS, Kaliki S.
europepmc   +1 more source