Results 71 to 80 of about 315,290 (253)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Prenatal diagnosis of cranio-orbito-maxillary neuroblastoma: a case report

Case Reports in Perinatal Medicine
Congenital neuroblastoma is one of the most common solid tumors in the perinatal period; however, primary cranial localization with prenatal onset is extremely rare.
Polat Busra Berfin, Melekoglu Rauf, Guresci Servet   +2 more
doaj   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

A review of the Groote Schuur hospital experience of low-velocity non-missile penetrating orbital and transorbital stab wounds [PDF]

, 2004
Includes bibliographical references.The aim of this study is to perform a retrospective review of all cases of low-velocity non-missile penetrating orbital trauma with intracranial complications presenting at Groote Schuur Hospital over the 5 year period
Welman, Chris
core   +1 more source

Orbital Plasmacytoma in an Elderly Patient With Multiple Myeloma

Orbital plasmacytomas are exceedingly rare neoplasms characterized by the proliferation of monoclonal plasma cells in the orbital soft tissues. Their presentation and clinical course can be diverse, making early diagnosis and management challenging. This
Qureshi, Pir Abdul Ahad Aziz, Bollineni, Vikram Rao, Aloui, Salma, Salma Aloui   +3 more
core   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Case Report: Primary epithelioid sarcoma of orbit: first case in Asia and literature review

Frontiers in Oncology
BackgroundEpithelioid sarcoma is an exceedingly rare malignant soft tissue neoplasm with unclear histogenesis and distinctive epithelioid morphology. Primary epithelioid sarcoma of orbit represents an extremely rare clinical entity, with only isolated ...
Guang Yang, Guang Yang, Jingping Yuan, Fangfang Chen, Honglin Yan, Wen Liu   +5 more
doaj   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Diagnostic and Therapeutic Management of Primary Orbital Neuroendocrine Tumors (NETs): Systematic Literature Review and Clinical Case Presentation

Biomedicines
Background: The ocular involvement of neuroendocrine neoplasms (NENs) is uncommon and mainly represented by metastases from gastrointestinal and lung neuroendocrine tumors.
Giulia Arrivi, Monia Specchia, Emanuela Pilozzi, Maria Rinzivillo, Damiano Caruso, Curzio Santangeli, Daniela Prosperi, Anna Maria Ascolese, Francesco Panzuto, Federica Mazzuca   +9 more
doaj   +1 more source