Results 51 to 60 of about 551,491 (329)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Fundamental photon orbits in the double Schwarzschild space-time
European Physical Journal C: Particles and Fields, 2022 We consider photon orbits in the space-time consisting of two identical Schwarzschild black holes in static equilibrium. In particular, we focus on fundamental photon orbits – bound photon orbits that do not fall into either black hole or go to infinity.
Zeyu Fan, Edward Teo
doaj +1 more source
Existence and Control of Special Orbits around Asteroid 4 Vesta
Aerospace, 2022 This paper focuses on the existence and control of particular types of orbits around asteroid 4 Vesta, including Sun-synchronous orbits, orbits at the critical inclination, repeating ground-track orbits, and stationary orbits.
Bo Ren +3 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Remote Sensing, 2021 We investigate the estimation of the fractional cycle biases (FCBs) for GPS triple-frequency uncombined precise point positioning (PPP) with ambiguity resolution (AR) based on the IGS ultra-rapid predicted (IGU) orbits. The impact of the IGU orbit errors
Lizhong Qu +6 more
doaj +1 more source
Orbital and strongly orbital spaces
Journal of Mathematical Analysis and Applications, 2014 Submitted to JMAA.
openaire +4 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Trapped and escaping orbits in an axially symmetric galactic-type potential
, 2012 In the present article, we investigate the behavior of orbits in a time independent axially symmetric galactic type potential. This dynamical model can be considered to describe the motion in the central parts of a galaxy, for values of energies larger ...
Zotos, Euaggelos E.
core +1 more source
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
Rational Orbits around Charged Black Holes
, 2010 We show that all eccentric timelike orbits in Reissner-Nordstr\"{o}m spacetime can be classified using a taxonomy that draws upon an isomorphism between periodic orbits and the set of rational numbers.
Janna Levin +3 more
core +1 more source