Results 81 to 90 of about 28,761 (248)

E-Orbit Functions

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2008
We review and further develop the theory of $E$-orbit functions. They are functions on the Euclidean space $E_n$ obtained from the multivariate exponential function by symmetrization by means of an even part $W_{e}$ of a Weyl group $W$, corresponding to ...
Jiri Patera, Anatoliy U. Klimyk
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

On the Action of a Subgroup of the Modular Group on Imaginary Quadratic Number Fields

open access: yesAxioms
Consider the modular group PSL(2,Z)=⟨x,y|x2=y3=1⟩ generated by the transformations x:z↦−1/z and y:z↦(z−1)/z. Let H be the proper subgroup ⟨y,v|y3=v3=1⟩ of PSL(2,Z), where v=xyx.
Abdulaziz Deajim
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A large-deformation mechanical-thermal-chemical coupling model for thermal barrier coatings incorporating strain gradient effects

open access: yesForces in Mechanics
The growth of the thermally grown oxide (TGO), formed during the oxidation of thermal barrier coatings (TBCs) in advanced gas turbine engines, exhibits a pronounced size effect as the thickness approaches its grain size.
Xuefei Ma   +3 more
doaj   +1 more source

Capillary orbits

open access: yesNature Communications, 2019
It is known that liquid drops can be levitated by continuous vapour flow above a liquid surface. Here the authors combine the ultra-low friction provided by the bath with the interaction force between two drops due to interface deformations to study the ...
Anaïs Gauthier   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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