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Inhibition of Orbivirus Replication by Aurintricarboxylic Acid [PDF]

International Journal of Molecular Sciences, 2020
Bluetongue virus (BTV) and African horse sickness virus (AHSV) are vector-borne viruses belonging to the Orbivirus genus, which are transmitted between hosts primarily by biting midges of the genus Culicoides. With recent BTV and AHSV outbreaks causing epidemics and important economy losses, there is a pressing need for efficacious drugs to treat and ...
Sérgio Utrilla-Trigo, Eva Calvo-Pinilla, Luis Jiménez-Cabello   +2 more
exaly   +5 more sources

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Isolation and characterization of orbivirus genotypic variants

Virus Research, 1987
Orbivirus variants containing either RNA deletions or concatemeric RNAs have been isolated. A variant of Ibaraki virus (a member of the epizootic hemorrhagic disease of deer serogroup) contained an RNA 9 segment which had terminal sequences identical to RNA 9 of wild type virus but was approximately 140 base pairs (bp) shorter.
B T Eaton, Allan R Gould
exaly   +3 more sources

In vivo and in vitro propagation and transmission of Toggenburg orbivirus

Research in Veterinary Science, 2011
The Toggenburg orbivirus (TOV), a recently discovered virus related to bluetongue virus (BTV), has been identified in goats in Switzerland, Italy and Germany. Isolation of TOV in vitro has not yet been achieved and the transmission mechanisms are still unknown. In the experimental infection of pregnant goats described here, TOV could not be detected in
Christian Kaufmann, Dolores Gavier-Widén, Martin A Hofmann   +2 more
exaly   +3 more sources

Identification and characterization of a novel orbivirus, Yonaguni orbivirus, isolated from cattle on the westernmost island of Japan

Archives of Virology, 2020
A novel orbivirus (genus Orbivirus, family Reoviridae), designated Yonaguni orbivirus (YONOV), was isolated from bovine blood collected on a subtropical island of Japan in 2015. The YONOV genome (20,054 nucleotides in total) has a coding arrangement similar to those of mosquito-borne orbiviruses. YONOV has a close genetic relationship to mosquito-borne
Katsunori Murota, Yuto Suda, Hiroaki Shirafuji, Keiko Ishii, Yoshito Katagiri, Moemi Suzuki, Daisuke Kobayashi, Haruhiko Isawa, Shogo Tanaka, Tohru Yanase   +9 more
openaire   +2 more sources

Characterisation of Wongorr virus, an Australian orbivirus

Virus Research, 1996
Sequence analyses of VP3 gene segments of Wongorr virus isolates from the Northern Territory of Australia were compared with the cognate gene segments from Picola and Paroo River viruses. Previous serological investigations had demonstrated some relationships between these viruses, however VP3 gene sequence and phylogenetic analyses placed these ...
H, Parkes, A R, Gould
openaire   +2 more sources

The orbivirus genus. Diversity, structure, replication and phylogenetic relationships

Comparative Immunology, Microbiology and Infectious Diseases, 1994
The general properties of the orbiviruses have been examined at the physical, structural and molecular level. At the structural level, the orbiviruses (with the exception of the Kemerovo serogroup) appear similar. The replicative events are also similar, however differences in the ultrastructure of virus-specific structures and their association with ...
Allan R Gould, Alex D Hyatt
exaly   +3 more sources

Experimental infection of small ruminants with bluetongue virus expressing Toggenburg Orbivirus proteins

Veterinary Microbiology, 2016
Bluetongue virus (BTV) is the prototype orbivirus (Reoviridae family, genus Orbivirus) consisting of more than 24 recognized serotypes or neutralization groups. Recently, new BTV serotypes in goats have been found; serotype 25 (Toggenburg Orbivirusor TOV)
Piet A Van Rijn, Mieke A Maris-Veldhuis, René G P Van Gennip   +2 more
exaly   +3 more sources

Culicoides-borne Orbivirus epidemiology in a changing climate

Journal of Medical Entomology, 2023
Abstract Orbiviruses are of significant importance to the health of wildlife and domestic animals worldwide; the major orbiviruses transmitted by multiple biting midge (Culicoides) species include bluetongue virus, epizootic hemorrhagic disease virus, and African horse sickness virus.
Amy R Hudson, Bethany L McGregor, Phillip Shults, Marion England, Constance Silbernagel, Christie Mayo, Molly Carpenter, Tyler J Sherman, Lee W Cohnstaedt   +8 more
openaire   +2 more sources

Occurrence and spatial distribution of Toggenburg Orbivirus in Switzerland

Small Ruminant Research, 2010
Abstract Recently, a new member of the Bluetongue virus (BTV) serogroup named Toggenburg Orbivirus (TOV) in goats from Switzerland has been described. The epidemiology and host range of TOV are currently unknown. Since TOV causes cross-reactions in laboratory tests used for BTV diagnosis, this study was carried out in order to determine the spatial ...
Valerie Chaignat, HEINZPETER Schwermer, Carrie Batten   +2 more
exaly   +2 more sources