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Experimental BTV-3 and BTV-8 Infection of Culicoides sonorensis Biting Midges

Parasites and Vectors
Background Bluetongue virus (BTV) is the etiologic agent of a major infectious disease of livestock and is transmitted between its ruminant hosts by Culicoides biting midges. The first outbreak ever recorded in central Europe was caused by serotype BTV-8
Bernd Hoffmann, Kerstin Wernike, Martin Beer   +2 more
exaly   +5 more sources

Evaluation of Bluetongue Virus (BTV) Antibodies for the Immunohistochemical Detection of BTV and Other Orbiviruses [PDF]

Microorganisms, 2020
The detection of bluetongue virus (BTV) antigens in formalin-fixed tissues has been challenging; therefore, only a limited number of studies on suitable immunohistochemical approaches have been reported.
Fabian Z. X. Lean, Jean Payne, Jennifer Harper, Joanne Devlin, David T. Williams, John Bingham   +5 more
doaj   +7 more sources

Attenuation of Bluetongue Virus (BTV) in an in ovo Model Is Related to the Changes of Viral Genetic Diversity of Cell-Culture Passaged BTV [PDF]

Viruses, 2019
The embryonated chicken egg (ECE) is routinely used for the laboratory isolation and adaptation of Bluetongue virus (BTV) in vitro. However, its utility as an alternate animal model has not been fully explored.
Fabian Z. X. Lean, Matthew J. Neave, John R. White, Jean Payne, Teresa Eastwood, Jemma Bergfeld, Antonio Di Rubbo, Vittoria Stevens, Kelly R. Davies, Joanne Devlin, David T. Williams, John Bingham   +11 more
doaj   +6 more sources

BTV Remodels the oISG15-Association Proteome. [PDF]

Microorganisms
ISG15 is an interferon-induced ubiquitin-like protein that exerts diverse functions during viral infection. We previously reported that ovine ISG15 (oISG15) promoted bluetongue virus (BTV) replication by stabilizing viral NS1 and VP4 in an ISGylation-independent manner, although the mechanism remained unknown.
Kang D, Gao Q, Zhang M, Ha R, Hu X, Li M, Chen Z, Bao S.   +7 more
europepmc   +4 more sources

Isolation and Cultivation of a New Isolate of BTV-25 and Presumptive Evidence for a Potential Persistent Infection in Healthy Goats

Viruses, 2020
Recently, several so-called “atypical” Bluetongue virus (BTV) serotypes were discovered, including BTV-25 (Toggenburg virus), in Switzerland. Most “atypical” BTV were identified in small ruminants without clinical signs. In 2018, two goats from a holding
Bernd Hoffmann, Martin Beer
exaly   +3 more sources

Molecular Epidemiological Characteristics and Genetic Evolution of Bluetongue Virus in Yunnan Province, China [PDF]

Microorganisms
Bluetongue is an insect-borne disease of ruminants caused by the Bluetongue virus (BTV). It is primarily transmitted through the bites of Culicoides midges and is widely distributed in tropical, subtropical, and temperate regions around the world. Due to
Zhenxing Yang, Yuwen He, Yongkang Li, Jinxin Meng, Nan Li, Susheng Li, Haisheng Miao, Jianling Song   +7 more
doaj   +2 more sources

Genome Constellations Recovered Following In Vitro Co-Infection and Serial Passage of Bluetongue Virus Serotypes 1 and 16 [PDF]

Viruses
Bluetongue virus (BTV) is a segmented RNA virus capable of genome reassortment during co-infection. We characterized genome constellations recovered after co-infection of Vero cells with western BTV-1 and eastern BTV-16 strains followed by three serial ...
Gloria Plebani, Anna Salvaggiulo, Federica Pizzurro, Liana Teodori, Alessandra Leone, Lorenza Brandimarte, Mariassunta Iannetta, Simone Pulsoni, Giacomo Vecchiato, Claudia Casaccia, Alessio Lorusso   +10 more
doaj   +2 more sources

High Seroprevalence of Bluetongue Virus Serotype 3 in Belgian Cattle and Sheep After the 2024 Epidemic [PDF]

Viruses
To monitor the epidemiological situation of bluetongue virus (BTV) in Belgium, a national surveillance programme was conducted during the 2024–2025 winter season.
Mickaël Cargnel, Xavier Simons, Ilse De Leeuw, Nick De Regge, Jean-Baptiste Hanon   +4 more
doaj   +2 more sources

Development of Freeze-dried Reagents based Multiplex PCR Assay for the Detection of Common and Emerging Abortion-causing Pathogens

Journal of Pure and Applied Microbiology, 2021
Bovine abortion is economically one of the most devastating problems faced by dairy farmers. Apart from non-infectious causes, several infectious pathogens are responsible for abortions, which sometimes manifests as abortion storms.
Pallavi Deol, Sukdeb Nandi, Vishal Chander, Chandan Prakash, Sonalika Mahajan, Safoora Kashafi, Ashwini R. Chaple, Saima M. Ganie, Karam Pal Singh, Gaurav Kumar Sharma   +9 more
doaj   +1 more source

Diversity and seasonal abundance of Culicoides (Diptera, Ceratopogonidae) in Shizong County, Yunnan Province, China

Parasite, 2022
Culicoides (Diptera, Ceratopogonidae) are small biting midges, some of which are vectors for animal associated arboviruses such as bluetongue virus (BTV) and Akabane virus (AKAV).
Duan Ying Liang, Bellis Glenn, Liu Bing Gang, Li Le   +3 more
doaj   +1 more source