Results 21 to 30 of about 17,564 (206)

A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus [PDF]

, 2014
Bluetongue is one of the major infectious diseases of ruminants and is caused by Bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct serotypes. Here, we describe the development of a vaccine platform for BTV.
Brunet, Silvie, Hamers, Claude, Hudelet, Pascal, Nunes, Sandro Filipe, Palmarini, Massimo, Ratinier, Maxime, Shaw, Andrew   +6 more
core   +2 more sources

Risk‐based serological survey of bluetongue and the first evidence of bluetongue virus serotype 26 circulation in Tunisia

Veterinary Medicine and Science, 2022
Background Bluetongue (BT), a vector‐borne disease of wild and domestic ruminants, is responsible for severe economic losses in flocks. To reduce this impact, a surveillance and control plan was implemented in Tunisia.
Kalthoum Sana, Sghaier Soufien, Ben Hassine Thameur, Teodori Liana, Spedicato Massimo, Guesmi Kaouther, Gharbi Raja, Hajlaoui Haikel, Bel Haj Mohamed Bassem, Khalfaoui Wiem, Lachtar Monia, Ben Salem Ameni, Fatnassi Naouel, Dhaouadi Anissa, Ben Ali Mehdi, Thabet Sarah, Seghaier Chedia, Savini Giovanni, Hammami Salah   +18 more
doaj   +1 more source

In Vitro Reassortment between Endemic Bluetongue Viruses Features Global Shifts in Segment Frequencies and Preferred Segment Combinations

Microorganisms, 2021
Bluetongue virus (BTV) is an arthropod-borne pathogen that is associated with sometimes severe disease in both domestic and wild ruminants. Predominantly transmitted by Culicoides spp.
Jennifer Kopanke, Justin Lee, Mark Stenglein, Christie Mayo   +3 more
doaj   +1 more source

Long-term dynamics of bluetongue virus in wild ruminants: relationship with outbreaks in livestock in Spain, 2006-2011.

PLoS ONE, 2014
Wild and domestic ruminants are susceptible to Bluetongue virus (BTV) infection. Three BTV serotypes (BTV-4, BTV-1 and BTV-8) have been detected in Spain in the last decade.
Cristina Lorca-Oró, Jorge Ramón López-Olvera, Francisco Ruiz-Fons, Pelayo Acevedo, Ignacio García-Bocanegra, Álvaro Oleaga, Christian Gortázar, Joan Pujols   +7 more
doaj   +1 more source

Increased Clinical Signs and Mortality in IFNAR^(−/−) Mice Immunised with the Bluetongue Virus Outer-Capsid Proteins VP2 or VP5, after Challenge with an Attenuated Heterologous Serotype

Pathogens, 2023
Bluetongue is an economically important disease of domesticated and wild ruminants caused by bluetongue virus (BTV). There are at least 36 different serotypes of BTV (the identity of which is determined by its outer-capsid protein VP2), most of which are
Houssam Attoui, Fauziah Mohd Jaafar, Baptiste Monsion, Bernard Klonjkowski, Elizabeth Reid, Petra C. Fay, Keith Saunders, George Lomonossoff, David Haig, Peter P. C. Mertens   +9 more
doaj   +1 more source

Virus and host factors affecting the clinical outcome of bluetongue virus infection [PDF]

, 2014
Bluetongue is a major infectious disease of ruminants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides. Here, we assessed virus and host factors influencing the clinical outcome of BTV infection using a single experimental ...
Caporale, Marco, Di Gialleonorado, Luigina, Di Ventura, Mauro, Janowicz, Anna, Mertens, Peter, Palmarini, Massimo, Savini, Giovanni, Shaw, Andrew, Van Rijn, Piet A., Wilkie, Gavin   +9 more
core   +3 more sources

Testicular degeneration and infertility following arbovirus infection [PDF]

, 2018
Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria, Ligios, Ciriaco, Maestrale, Caterina, Manunta, Daniela, Meloni, Giorgio, Melzi, Eleonora, Oggiano, Annalisa, Palmarini, Massimo, Pintus, Davide, Puggioni, Giantonella, Rocchigiani, Angela Maria, Savini, Giovanni   +11 more
core   +1 more source

Seroprevalence of bluetongue serotype 8 in cattle in the Netherlands in spring 2007, and its consequences [PDF]

, 2008
A cross-sectional study was carried out in spring 2007, at the end of the first bluetongue outbreak season, to determine the geographical spread of bluetongue virus serotype 8 (BTV-8) infection in cattle in the Netherlands and the consequences for some ...
Berends, I.M.G.A., Elbers, A.R.W., Langen, H., Schaik, G., van, Vellema, P.   +4 more
core   +2 more sources

Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study

Pathogens, 2022
Bluetongue virus (BTV), an arbovirus of ruminants, is a causative agent of numerous epidemics around the world. Due to the emergence of novel reassortant BTV strains and new outbreaks, there is an unmet need for efficacious antivirals.
Lijo John, Caroline Vernersson, Hyesoo Kwon, Ulrich Elling, Josef M. Penninger, Ali Mirazimi   +5 more
doaj   +1 more source

Role of wild ruminants in the epidemiology of bluetongue virus serotypes 1, 4 and 8 in Spain

Veterinary Research, 2011
Although the importance of wild ruminants as potential reservoirs of bluetongue virus (BTV) has been suggested, the role played by these species in the epidemiology of BT in Europe is still unclear.
García-Bocanegra Ignacio, Arenas-Montes Antonio, Lorca-Oró Cristina, Pujols Joan, González Miguel, Napp Sebastián, Gómez-Guillamón Félix, Zorrilla Irene, Miguel Elena, Arenas Antonio   +9 more
doaj   +1 more source