Results 21 to 30 of about 7,724 (208)

Transplacental transmission of Bluetongue virus serotype 1 and serotype 8 in sheep: virological and pathological findings. [PDF]

PLoS ONE, 2013
The Bluetongue virus serotype 8 (BTV-8) strain, which emerged in Europe in 2006, had an unusually high ability to cause foetal infection in pregnant ruminants.
Mirjam T W van der Sluijs, Dianne P H Schroer-Joosten, Aicha Fid-Fourkour, Mieke P Vrijenhoek, Isolde Debyser, Véronique Moulin, Rob J M Moormann, Abraham J de Smit   +7 more
doaj   +1 more source

Vaccination With Recombinant Adenoviruses Expressing the Bluetongue Virus Subunits VP7 and VP2 Provides Protection Against Heterologous Virus Challenge

Frontiers in Veterinary Science, 2021
Bluetongue virus (BTV) is the causative agent of a disease that affects domestic and wild ruminants and leads to critical economic losses. BTV is an arbovirus from the Reoviridae family that is typically transmitted by the bite of infected Culicoides ...
José Manuel Rojas, Diego Barba-Moreno, Miguel Avia, Noemí Sevilla, Verónica Martín   +4 more
doaj   +1 more source

Colostral transmission of BTV-8 antibodies from dairy cows six years after vaccination [PDF]

, 2018
Bluetongue virus (BTV) antibodies were analysed in 27 Swiss calves born in 2016 at the age of 16–19 days using competitive enzyme-linked-immunosorbent-assay (cELISA) and virus neutralization test (VNT) (animal trial permission number: 75684).
Büttner, Mathias, Mevissen, Meike, Ayrle, Hannah, Fricker, Raffael, Walkenhorst, Michael, Hofmann, Bernd, Kaske, Martin, Marinovic, Zlatko, Vögtlin, Andrea, Hoffmann, Bernd, Büttner M, Kaske M, Marinovic Z, Fricker R, Hoffmann B, Mevissen M, Vögtlin A, Ayrle H, Walkenhorst M   +18 more
core   +2 more sources

Increased Clinical Signs and Mortality in IFNAR^(−/−) Mice Immunised with the Bluetongue Virus Outer-Capsid Proteins VP2 or VP5, after Challenge with an Attenuated Heterologous Serotype

Pathogens, 2023
Bluetongue is an economically important disease of domesticated and wild ruminants caused by bluetongue virus (BTV). There are at least 36 different serotypes of BTV (the identity of which is determined by its outer-capsid protein VP2), most of which are
Houssam Attoui, Fauziah Mohd Jaafar, Baptiste Monsion, Bernard Klonjkowski, Elizabeth Reid, Petra C. Fay, Keith Saunders, George Lomonossoff, David Haig, Peter P. C. Mertens   +9 more
doaj   +1 more source

Long-term dynamics of bluetongue virus in wild ruminants: relationship with outbreaks in livestock in Spain, 2006-2011.

PLoS ONE, 2014
Wild and domestic ruminants are susceptible to Bluetongue virus (BTV) infection. Three BTV serotypes (BTV-4, BTV-1 and BTV-8) have been detected in Spain in the last decade.
Cristina Lorca-Oró, Jorge Ramón López-Olvera, Francisco Ruiz-Fons, Pelayo Acevedo, Ignacio García-Bocanegra, Álvaro Oleaga, Christian Gortázar, Joan Pujols   +7 more
doaj   +1 more source

Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study

Pathogens, 2022
Bluetongue virus (BTV), an arbovirus of ruminants, is a causative agent of numerous epidemics around the world. Due to the emergence of novel reassortant BTV strains and new outbreaks, there is an unmet need for efficacious antivirals.
Lijo John, Caroline Vernersson, Hyesoo Kwon, Ulrich Elling, Josef M. Penninger, Ali Mirazimi   +5 more
doaj   +1 more source

Role of wild ruminants in the epidemiology of bluetongue virus serotypes 1, 4 and 8 in Spain

Veterinary Research, 2011
Although the importance of wild ruminants as potential reservoirs of bluetongue virus (BTV) has been suggested, the role played by these species in the epidemiology of BT in Europe is still unclear.
García-Bocanegra Ignacio, Arenas-Montes Antonio, Lorca-Oró Cristina, Pujols Joan, González Miguel, Napp Sebastián, Gómez-Guillamón Félix, Zorrilla Irene, Miguel Elena, Arenas Antonio   +9 more
doaj   +1 more source

Risk‐based serological survey of bluetongue and the first evidence of bluetongue virus serotype 26 circulation in Tunisia

Veterinary Medicine and Science, 2022
Background Bluetongue (BT), a vector‐borne disease of wild and domestic ruminants, is responsible for severe economic losses in flocks. To reduce this impact, a surveillance and control plan was implemented in Tunisia.
Kalthoum Sana, Sghaier Soufien, Ben Hassine Thameur, Teodori Liana, Spedicato Massimo, Guesmi Kaouther, Gharbi Raja, Hajlaoui Haikel, Bel Haj Mohamed Bassem, Khalfaoui Wiem, Lachtar Monia, Ben Salem Ameni, Fatnassi Naouel, Dhaouadi Anissa, Ben Ali Mehdi, Thabet Sarah, Seghaier Chedia, Savini Giovanni, Hammami Salah   +18 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus. [PDF]

Adv Sci (Weinh)
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Guan J, Zhou D, Shao R, Liu X, Peng J, Huang Y, Qi S, Xi C, Wang M, Sun B, Qi Y, Yin X.   +11 more
europepmc   +2 more sources

Bluetongue Virus Infection of Goats: Re-Emerged European Serotype 8 vs. Two Atypical Serotypes

Viruses, 2022
In recent years, numerous atypical Bluetongue virus (BTV) strains have been discovered all around the world. Atypical BTV strains are phylogenetically distinct from the classical BTV serotypes 1–24 and differ in terms of several biological features.
Christina Ries, Martin Beer, Bernd Hoffmann   +2 more
doaj   +1 more source