Origin recognition complex subunit 1 functions as an oncogenic driver and therapeutic target in cancer. [PDF]
Ding Y, Cai S, Cai J, Wang Z, Zhu Z.
europepmc +1 more source
A cross-species rescue by mating method to interrogate gene essentiality across the <i>Saccharomyces</i> genus. [PDF]
Wang TK, Keller A, Kunjo O, Dunham MJ.
europepmc +1 more source
Geminin inhibits DNA replication licensing by sterically blocking CDT1-MCM2 interactions. [PDF]
Tomkins J +13 more
europepmc +1 more source
Molecular impacts of Meier-Gorlin syndrome mutations on human origin licensing. [PDF]
Yang R, Hunker O, Kim J, Bleichert F.
europepmc +1 more source
DNA bending mediated by ORC is essential for replication licensing in budding yeast. [PDF]
Lam WH +11 more
europepmc +1 more source
Cell cycle regulation has shaped replication origins in budding yeast. [PDF]
Lim CT +9 more
europepmc +1 more source
MCM double hexamer loading visualized with human proteins. [PDF]
Weissmann F +7 more
europepmc +1 more source
Regulation of replication origin licensing by ORC phosphorylation reveals a two-step mechanism for Mcm2-7 ring closing. [PDF]
Amasino AL +4 more
europepmc +1 more source
Multiple mechanisms for licensing human replication origins. [PDF]
Yang R, Hunker O, Wise M, Bleichert F.
europepmc +1 more source

