Results 121 to 130 of about 659 (130)

Transcriptional response of the terpenoid indole alkaloid pathway to the overexpression of ORCA3 along with jasmonic acid elicitation of Catharanthus roseus hairy roots over time

Metabolic Engineering, 2009
Jasmonic acid (JA) activates the transcriptional regulator ORCA3, which has a role in regulating the terpenoid indole alkaloid (TIA) pathway within Catharanthus roseus. The TIA pathway leads to the production of the anticancer drugs vinblastine and vincristine.
Christie A M Peebles, Ka-Yiu San
exaly   +3 more sources

Overexpression of transcriptional factor ORCA3 increases the accumulation of catharanthine and vindoline in Catharanthus roseus hairy roots

Russian Journal of Plant Physiology, 2011
The AP2/ERF-domain transcription factor ORCA3 of Catharanthus roseus has been recognized earlier as a regulator of the expression of some important genes involved in the terpenoid indole alkaloid (TIA) biosynthetic pathway in C. roseus cells. Therefore, this factor was postulated to play an important role for the biosynthesis of secondary metabolites ...
K. X. Tang, D. H. Liu, Y. L. Wang, L. J. Cui, W. W. Ren, X. F. Sun   +5 more
exaly   +2 more sources

Overexpression of G10H and ORCA3 in the hairy roots of Catharanthus roseus improves catharanthine production

Plant Cell Reports, 2010
A number of genes that function in the terpenoid indole alkaloids (TIAs) biosynthesis pathway have been identified in Catharanthus roseus. Except for the geraniol 10-hydroxylase (G10H) gene, which encodes a cytochrome P450 monooxygenase, several of these genes are up-regulated by ORCA3, a jasmonate-responsive APETALA2 (AP2)-domain transcript factor. In
Cui-Ting, Wang, Hua, Liu, Xiao-Shu, Gao, Hong-Xia, Zhang   +3 more
exaly   +3 more sources

Transcriptomic Analyses of Cathatranthus roseus Hairy Roots Overexpressing CrMYC2 and ORCA3 and Roles of Cross-Family Transcription Factor Interaction in Terpenoid Indole Alkaloid Biosynthesis

2017
Catharanthus roseus (Madagascar periwinkle), is a well-known medicinal plant that produces a vast array of terpenoid indole alkaloids (TIAs), including two anticancer compounds vinblastine and vincristine. Industrial scale production of TIAs is hampered by the difficulties of total chemical synthesis of these compounds and the fragmented knowledge on ...
openaire   +1 more source

Mutually Regulated AP2/ERF Gene Clusters Modulate Biosynthesis of Specialized Metabolites in Plants

Plant Physiology, 2020
Priyanka Paul, Barunava Patra, Sitakanta Pattanaik   +2 more
exaly  

Identification of a Bipartite Jasmonate-Responsive Promoter Element in the Catharanthus roseus ORCA3 Transcription Factor Gene That Interacts Specifically with AT-Hook DNA-Binding Proteins

Plant Physiology, 2007
Marina Soares e Silva, Giancarlo Pasquali, Johan Memelink   +2 more
exaly  

APETALA2/ETHYLENE RESPONSE FACTOR and basic helix–loop–helix tobacco transcription factors cooperatively mediate jasmonate‐elicited nicotine biosynthesis

Plant Journal, 2011
Laurens Pauwels, John D Hamill, Jonas Goossens   +2 more
exaly  

Transcriptional response of the catharanthine biosynthesis pathway to methyl jasmonate/nitric oxide elicitation in Catharanthus roseus hairy root culture

Applied Microbiology and Biotechnology, 2010
Mei-Liang Zhou
exaly  

Function of AP2/ERF Transcription Factors Involved in the Regulation of Specialized Metabolism in Ophiorrhiza pumila Revealed by Transcriptomics and Metabolomics

Frontiers in Plant Science, 2016
Amit Rai, Hideyuki Suzuki, Ryo Nakabayashi   +2 more
exaly  

Methyl jasmonic acid induced expression pattern of terpenoid indole alkaloid pathway genes in Catharanthus roseus seedlings

Plant Growth Regulation, 2010
exaly