Results 51 to 60 of about 7,638 (241)

Distinct actions of testicular endocrine and lumicrine signaling on the proximal epididymal transcriptome

Reproductive Biology and Endocrinology
The epididymal function and gene expression in mammals are under the control of the testis. Sex steroids are secreted from the testis and act on the epididymis in an endocrine manner.
Daiji Kiyozumi
doaj   +1 more source

The Similarities and Differences between the Effects of Testosterone and DHEA on the Innate and Adaptive Immune Response

Biomolecules, 2022
Androgens are steroids that modulate various processes in the body, ranging from reproduction, metabolism, and even immune response. The main androgens are testosterone, dihydrotestosterone (DHT) and dehydroepiandrosterone (DHEA). These steroids modulate
Fidel Orlando Buendía-González, Martha Legorreta-Herrera   +1 more
doaj   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Effects of orchidectomy (Orx), vitamin E and aspirin on trabecular microarchitectural parameters of distal femur.

, 2018
Effects of orchidectomy (Orx), vitamin E and aspirin on trabecular microarchitectural parameters of distal femur.
Bahram H. Arjmandi (5897105), Elizabeth M. Foley (5897102), Sheau C. Chai (5897099)   +2 more
core   +1 more source

Orchidectomy Ameliorates the Vascular Hypertrophic Effect of A High Salt Diet in Sprague-Dawley Rats [PDF]

, 2016
Sodium overload, which is present in a high salt diet (HSD), induces hypertension by mechanisms that include change in the shear stress and geometric modifications of the blood vessels.
Anigbogu, CN, Vineetha, VP, Oloyo, AK, Sofola, OA   +3 more
core   +1 more source

Dehydroepiandrosterone (DHEA) Improves the Metabolic and Haemostatic Disturbances in Rats with Male Hypogonadism

Scientia Pharmaceutica, 2022
Objectives: The current work was designed to study the effect of dehydroepiandrosterone (DHEA) on glucose homeostasis, liver functions and hemostatic disturbances in a rat model of bilateral orchidectomy (ORCH).
Sally M. Safwat, Abdelaziz M. Hussein, Elsayed A. Eid, Mohamed S. Serria, Basem H. Elesawy, Hussein F. Sakr   +5 more
doaj   +1 more source

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

Effects of orchidectomy (Orx), vitamin E and aspirin on biomarkers of bone metabolism.

, 2018
Effects of orchidectomy (Orx), vitamin E and aspirin on biomarkers of bone metabolism.
Bahram H. Arjmandi (5897105), Elizabeth M. Foley (5897102), Sheau C. Chai (5897099)   +2 more
core   +1 more source

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

Effects of orchidectomy (Orx), vitamin E and aspirin on food intake, body and coagulating gland weights.

, 2018
Effects of orchidectomy (Orx), vitamin E and aspirin on food intake, body and coagulating gland weights.
Bahram H. Arjmandi (5897105), Elizabeth M. Foley (5897102), Sheau C. Chai (5897099)   +2 more
core   +1 more source