Results 101 to 110 of about 11,363,143 (293)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Explicit solutions for a system of first-order partial differential equations

Electronic Journal of Differential Equations, 2008
In this paper we construct explicit weak solutions of a system of two partial differential equations in the quarter plane ${(x,t):x>0,t>0}$ with initial conditions at $t=0$ and a weak form of Dirichlet boundary conditions at $x=0$. This system was
Kayyunnapara Thomas Joseph
doaj  

Stability Conditions of Second Order Integrodifferential Equations with Variable Delay

Abstract and Applied Analysis, 2014
We investigate integrodifferential functional differential equations ẍ+f(t,x,ẋ)ẋ+∫t-r(t)t‍a(t,s)g(x(s))ds=0 with variable delay. By using the fixed point theory, we obtain conditions which ensure that the zero solution of this equation is stable under
Dingheng Pi
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Nonlinear Coupled Fractional Order Systems with Integro-Multistrip-Multipoint Boundary Conditions

International Journal of Analysis and Applications, 2019
We study the existence and uniqueness of solutions for a nonlinear system of coupled fractional differential equations equipped with nonlocal coupled integro-multistrip-multipoint boundary conditions.
Bashir Ahmad, Ahmed Alsaedi, Sotiris K. Ntouyas   +2 more
doaj   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Explicit solutions for a system of first-order partial differential equations-II

Electronic Journal of Differential Equations, 2011
In this note we give an explicit formula for the solution of conservative form of a system studied in a previous article [6], in the domain ${(x,t):x>0,t>0}$ with initial conditions at $t=0$ and with Bardos Leroux Nedelec boundary conditions at $x=0$.
Kayyunnapapra Thomas Joseph, Manas Ranjan Sahoo   +1 more
doaj  

First-Order Conditions for C0,1 Constrained vector optimization [PDF]

For a Fritz John type vector optimization problem with C0,1 data we define different type of solutions, give their scalar characterizations applying the so called oriented distance, and give necessary and sufficient first order optimality conditions in ...
Ginchev Ivan, Guerraggio Angelo, Rocca Matteo   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

On transparent boundary conditions for the high--order heat equation

, 2013
In this paper we develop an artificial initial boundary value problem for the high-order heat equation in a bounded domain $\Omega$. It is found an unique classical solution of this problem in an explicit form and shown that the solution of the ...
Suragan, Durvudkhan, Tokmagambetov, Niyaz   +1 more
core