Results 91 to 100 of about 12,205,950 (252)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Design of Two-phase Slug Flow Microreactors Using Reduced Order Flow Model
Chemical Engineering TransactionsTwo-phase slug flow microreactors (SFMRs) are known to be capable of achieving more efficient mass and heat transfer than conventional reactors. However, no method for designing SFMRs has been established so far.
Takaki Yamazaki +2 more
doaj
Second order algorithm with convergence analysis for viscoelastic flow model
Journal of Mathematics in IndustryViscoelastic fluids have several applications in industry and technology, which has attracted a lot of investigation into their mathematical models. This paper presents the first-ever verifiable convergent second-order method, with complete theoretical ...
Chinedu Nwaigwe, Sanda Micula
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Arbitrage-free Limit Order Books and the Pricing of Order Flow Risk [PDF]
This paper builds on the landmark contribution of Glosten (1994) by treating the determination of limit order supply schedules as an exercise in asset pricing theory with the possible sizes of incoming market orders as the value-relevant states of nature,
Bruce Lehmann
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The currency that came in from the cold: Capital controls and the information content of order flow
, 2021 We analyse how capital controls affect FX microstructure, using as a case study the introduction and subsequent removal of controls in Iceland. We use a VAR of private order flow, Central Bank order flow and EURISK that allows for contemporaneous ...
Paolo Vitale +2 more
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
International Journal of Applied Mechanics and Engineering, 2015 An analysis of an oscillatory magnetohydrodynamic (MHD) convective flow of a second order (viscoelastic), incompressible, and electrically conducting fluid through a porous medium bounded by two infinite vertical parallel porous plates is presented.
B.P. Garg, K.D. Singh, A.K. Bansal
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Collapse of flow: probing the order of the phase transition [PDF]
, 2007 We discuss the present collective flow signals for the phase transition to the quark-gluon plasma (QGP) and the collective flow as a barometer for the equation of state (EoS). We emphasize the importance of the flow excitation function from 1 to 50A GeV:
Stöcker, Horst
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