Results 41 to 50 of about 12,205,950 (252)

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess   +5 more
wiley   +1 more source

Investigating the Impact of Order Flow Imbalance and Information Asymmetry on Treasury Bill Price Changes [PDF]

open access: yesتحقیقات مالی
ObjectiveThe information-based model is one of the prevalent frameworks in the market microstructure literature, examining trader behavior in the presence of information asymmetry and its subsequent impact on price formation.
Ali Namaki, Aysa Kazemi bavil
doaj   +1 more source

Multi-Level Order-Flow Imbalance in a Limit Order Book [PDF]

open access: yesMarket Microstructure and Liquidity, 2018
We study the multi-level order-flow imbalance (MLOFI), which is a vector quantity that measures the net flow of buy and sell orders at different price levels in a limit order book (LOB). Using a recent, high-quality data set for six liquid stocks on Nasdaq, we fit a simple, linear relationship between MLOFI and the contemporaneous change in mid-price.
Xu, K, Gould, MD, Howison, SD
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Second-order moment of kinetic theory of granular flow for multi-type particles [PDF]

open access: yes, 2023
In this study, a numerical method, second-order moment of kinetic theory of granular flow for multitype particles (SOM-KTGF-MP) is proposed. The SOM-KTGF is used for particle flow with higher concentration and high inertia where inter-particle collisions
Dan, Sun, Dan Sun
core   +1 more source

Utility of high-order scheme for unsteady flow simulations: Comparison with second-order tool

open access: yesJournal of Ocean Engineering and Science
The objective of this work is to investigate the utility and effectiveness of the high-order scheme for simulating unsteady turbulent flows. To achieve it, the studies are conducted from two perspectives: (i) the ability of different numerical schemes to
Peng Jiang   +4 more
doaj   +1 more source

High order mimetic difference simulation of unsaturated flow using Richards equation

open access: yesMathematics in Applied Sciences and Engineering, 2020
The vadose zone is the portion of the subsurface above the water table and its pore space usually contains air and water. Due to the presence of infiltration, erosion, plant growth, microbiota, contaminant transport, aquifer recharge, and discharge to ...
Angel Boada Velazco   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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