Results 31 to 40 of about 65,964 (245)
Targeted Learning of the Mean Outcome under an Optimal Dynamic Treatment Rule
Journal of Causal Inference, 2015 We consider estimation of and inference for the mean outcome under the optimal dynamic two time-point treatment rule defined as the rule that maximizes the mean outcome under the dynamic treatment, where the candidate rules are restricted to depend only ...
van der Laan Mark J. +1 more
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A Structural Characterization of Extended Correctness-Completeness in Classical Logic
Crítica, 2019 In this paper I deal with first order logic and axiomatic systems. I present the metalogical results that show the property of satisfying Modus Ponens as a necessary and sufficient condition for the extended completeness of the system, and to the ...
José Alfredo Amor
doaj +1 more source
BMC Bioinformatics, 2009 Background For gene expression data obtained from a time-course microarray experiment, Liu et al. 1 developed a new algorithm for clustering genes with similar expression profiles over time.
Umbach David M +2 more
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Order restricted Bayesian inference for exponential simple step-stress model [PDF]
Communications in Statistics - Simulation and Computation, 2016 Step-stress model has received a considerable amount of attention in recent years. In the usual step-stress experiment, stress level is allowed to increase at each step to get rapid failure of the experimental units. The expected lifetime of the experimental unit is shortened as the stress level increases.
Debashis Samanta +3 more
openaire +1 more source
Molecular Investigation Confirms Myotis Genus Bats as Common Hosts of Polychromophilus in Brazil
Microorganisms, 2023 Plasmodium spp. and some other blood parasites belonging to the order Haemosporida are the focus of many epidemiological studies worldwide. However, haemosporidian parasites from wild animals are largely neglected in scientific research.
Bruno da Silva Mathias +13 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Pleistocene niche stability and lineage diversification in the subtropical spider Araneus omnicolor (Araneidae). [PDF]
PLoS ONE, 2015 The influence of Quaternary climate oscillations on the diversification of the South American fauna is being increasingly explored. However, most of these studies have focused on taxa that are endemic to tropical environments, and relatively few have ...
Elen A Peres +6 more
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Robust Inference for Testing Order-Restricted Inference
Korean Journal of Applied Statistics, 2009 Classification of subjects with unknown distribution in small sample size setup may involve order-restricted constraints in multivariate parameter setups. Those problems makes optimality of conventional likelihood ratio based statistical inferences not feasible.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source