Results 71 to 80 of about 65,964 (245)
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Analysis of epistatic interactions and fitness landscapes using a new geometric approach
BMC Evolutionary Biology, 2007 Background Understanding interactions between mutations and how they affect fitness is a central problem in evolutionary biology that bears on such fundamental issues as the structure of fitness landscapes and the evolution of sex.
Elena Santiago F +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Ecological IndicatorsPerennial grain crops have been proposed as a more sustainable alternative to annual counterparts given their potential to replicate natural ecosystem services when managed correctly while requiring less external input than annual agriculture.
Noah L. Ring, Nathaniel A. Brunsell
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source
The Nature of Political Jurisprudence in Terms of Jurisprudential Proposition [PDF]
Journal of Islamic Political StudiesThe present study has been aims to accurately explain the nature and scope of political jurisprudence in terms of its fundamental unit, namely the "jurisprudential proposition." I argue that the ambiguities and divergence of opinions existing in the ...
Hadi Jalali Asl
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch +6 more
wiley +1 more source
Transformers for Stratified Spectropolarimetric Inversion: Proof of Concept
The Astrophysical JournalSolar spectropolarimetric inversion—inferring atmospheric conditions from the Stokes vector—is a key diagnostic tool for understanding solar magnetism, but traditional inversion methods are computationally expensive and sensitive to local minima ...
Ryan J. Campbell +2 more
doaj +1 more source