Results 131 to 140 of about 5,038,205 (326)

Stochastic inequalities involving past extropy of order statistics and past extropy of record values

open access: yesAIMS Mathematics
Recently, extropy has emerged as an alternative measure of uncertainty instead of entropy. When it comes to quantifying uncertainty regarding the remaining lifetime of a component, entropy has proven to be less effective.
Mansour Shrahili   +2 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Moments of Order Statistics

open access: yesThe Annals of Statistics, 1973
Let $X_{(i\mid n)}$ be the $i$th smallest order statistic from a population with $\operatorname{pdf} f(x)$ and $\operatorname{cdf} F(x)$. When $\tilde{x}$ is the population median, $n$ is the sample size and $G(x) = F(x)(1 - F(x))$, the following are proved.
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Functions of Order Statistics

open access: yesThe Annals of Mathematical Statistics, 1972
Two theorems on the asymptotic normality of linear combinations of functions of order statistics are given. Theorem 1 requires a "smooth" scoring function but the underlying df need not be continuous even and can also depend on the sample size. Theorem 2 allows general scoring functions but places additional restrictions on the df.
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A New Lomax-G Family: Properties, Estimation and Applications

open access: yesEntropy
Given the increasing number of phenomena that demand interpretation and investigation, developing new distributions and families of distributions has become increasingly essential.
Hanan Baaqeel   +2 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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