Results 41 to 50 of about 11,862,847 (308)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Higher Order Statistics in a mmWave Propagation Environment
IEEE Access, 2019 A thorough measurement campaign in an indoor environment at the millimeter-wave band is carried out with an aim at characterizing the short-term fading channel in terms of its higher-order statistics.
Andre Antonio Dos Anjos +7 more
doaj +1 more source
Order Statistics and Their Applications to Quantitative Finance [PDF]
, 2008 This study concerns about order statistics and their applications to quantitative finance. So far, theories and applications of order statistics have been well developed and applied to many scientific fields ranging from conventional statistical problems
原田, 康平 +6 more
core
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On an Inequality for Order Statistics
The Annals of Mathematical Statistics, 1971 The problem of finding a Chebyshev type inequality for random variables with unknown or non-existent variance was considered by Z. W. Birnbaum (1970). In this present paper, a statistic, $T$, similar to, but simpler than Birnbaum's, is considered. The statistic is independent of location and scale parameters for families of bell-shaped distributions ...
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Complete convergence for arrays of minimal order statistics
International Journal of Mathematics and Mathematical Sciences, 2004 For arrays of independent Pareto random variables, this paper establishes complete convergence for weighted partial sums for the smaller order statistics within each row. This result improves on past strong laws.
André Adler
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On order statistics from nonidentical discrete random variables
Open Physics, 2016 In this study, pf and df of single order statistic of nonidentical discrete random variables are obtained. These functions are also expressed in integral form.
Yüzbaşı Bahadır +2 more
doaj +1 more source