Results 61 to 70 of about 5,049,636 (280)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Complete convergence for arrays of ratios of order statistics
Open Mathematics, 2019 Let {Xn,k, 1 ≤ k ≤ mn, n ≥ 1} be an array of independent random variables from the Pareto distribution. Let Xn(k) be the kth largest order statistic from the nth row of the array and set Rn,in,jn = Xn(jn)/Xn(in) where jn < in. The aim of this paper is to
Miao Yu +3 more
doaj +1 more source
How well do third-order aperture mass statistics separate E- and B-modes?
, 2014 With 3rd-order statistics of gravitational shear it will be possible to extract valuable cosmological information from ongoing and future weak lensing surveys which is not contained in standard 2nd-order statistics, due to the non-Gaussianity of the ...
Joachimi, Benjamin +2 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Using Order Texture Statistics to Classify Multi-Class Malware
Scientific Journal of King Faisal University: Basic and Applied SciencesThe most significant challenge in the security of information and communication networks is the escalating number of malware types, followed by the search for appropriate methods to protect systems against them, which is one of the most critical concerns
Raaed Fadhil Mohammed
doaj +1 more source
Exact distributions of order statistics from ln,p-symmetric sample distributions
Dependence Modeling, 2017 We derive the exact distributions of order statistics from a finite number of, in general, dependent random variables following a joint ln,p-symmetric distribution. To this end,we first review the special cases of order statistics fromspherical aswell as
Müller K., Richter W.-D.
doaj +1 more source
Statistica, 2019 In this article, we proposed and studied the inverted exponentiated gamma distribution (IEGD). IEGD is obtained by considering the inverse transformation of exponentiated gamma variate.
Abhimanyu Singh Yadav
doaj +1 more source
The Odds Generalized Gamma-G Family of Distributions: Properties, Regressions and Applications
Statistica, 2020 In this article, a new "odds generalized gamma-G" family of distributions, called the GG-G family of distributions, is introduced. We propose a complete mathematical and statistical study of this family, with a special focus on the Fréchet distribution ...
M. Arslan Nasir +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Towards an application of fourth-order shear statistics
Astronomy & AstrophysicsContext. Higher-order shear statistics contain part of the non-Gaussian information of the projected matter field and can therefore provide additional constraints on the cosmological parameters when combined with second-order statistics. Aims.
Silvestre-Rosello Elena +6 more
doaj +1 more source