Results 61 to 70 of about 1,234,268 (260)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Exact distributions of order statistics from ln,p-symmetric sample distributions
Dependence Modeling, 2017 We derive the exact distributions of order statistics from a finite number of, in general, dependent random variables following a joint ln,p-symmetric distribution. To this end,we first review the special cases of order statistics fromspherical aswell as
Müller K., Richter W.-D.
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Using Order Texture Statistics to Classify Multi-Class Malware
Scientific Journal of King Faisal University: Basic and Applied SciencesThe most significant challenge in the security of information and communication networks is the escalating number of malware types, followed by the search for appropriate methods to protect systems against them, which is one of the most critical concerns
Raaed Fadhil Mohammed
doaj +1 more source
Mathematical Modelling and Analysis, 2015 The Muth distribution is a continuous random variable introduced in the context of reliability theory. In this paper, some mathematical properties of the model are derived, including analytical expressions for the moment generating function, moments ...
Pedro Jodra +2 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Towards an application of fourth-order shear statistics
Astronomy & AstrophysicsContext. Higher-order shear statistics contain part of the non-Gaussian information of the projected matter field and can therefore provide additional constraints on the cosmological parameters when combined with second-order statistics. Aims.
Silvestre-Rosello Elena +6 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Image Stego Detection using Higher Order Statistics
مجلة النهرين للعلوم الهندسية, 2010 The basic approach taken here works by finding predictable higher-order statistics of natural images within a multi-scale decomposition, and then showing that embedded messages alter these statistics. A Fisher linear discriminant analysis is then used
Ammar Moufak J. Yousif +1 more
doaj