Results 91 to 100 of about 1,425,221 (328)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Multiplicative Mappings of Gamma Rings

open access: yesCumhuriyet Science Journal, 2019
Let Mi and Γi (i = 1, 2) be abelian groups such that Mi is a Γi-ring.An ordered pair (ϕ, φ) of mappings is called a multiplicative isomorphismof M1 onto M2 if they satisfy the following properties: (i) ϕ is a bijectivemapping from M1 onto M2, (ii) φ is a
Bruno Ferreira, Ruth N. Ferreira
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Sixth-order lie group integrators [PDF]

open access: yesJournal of Computational Physics, 1992
Symplectic integration is an approach to numerical integration of equations of motion that preserve invariants (like Hamiltonian systems). Here, the connection to Lie groups is exploited to derive a set of nonlinear equations the solutions of which determine sixth order symplectic integrators.
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On Ordered Groups [PDF]

open access: yesTransactions of the American Mathematical Society, 1945
Everett, C. J., Ulam, S.
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Periodic Ordered Permutation Groups and Cyclic Orderings

open access: yesJournal of Combinatorial Theory, Series B, 1995
It is shown that periodic ordered permutation groups satisfying certain extra conditions are very nearly simple. This is applied to several natural examples, such as the following. (i) If \(z\) denotes the map \(x \mapsto x + 1\) on \(\mathbb{R}\), and \(\text{Diff}(\mathbb{R})\) is the group of diffeomorphisms of \(\mathbb{R}\), then \(C_{\text{Diff}(\
Droste, M., Giraudet, M., Macpherson, D.
openaire   +1 more source

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