Results 91 to 100 of about 307,627 (269)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Topological lattice-ordered groups [PDF]

open access: yesPacific Journal of Mathematics, 1979
Several types of hulls and completions of lattice ordered groups have been obtained by algebraic methods. In this paper is laid some groundwork for the application of topological and uniform-space concepts to the same end by setting forth those links—topological, algebraic and semantic— between a topological lattice ordered group H and a topologically ...
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Covalent Organic Framework with 3D Ordered Channel and Multi-Functional Groups Endows Zn Anode with Superior Stability

open access: yesNano-Micro Letters
Highlights A fluorinated zincophilic covalent organic framework (COF-S-F) with sulfonic acid group (-SO3H) is prepared on the surface of Zn anode, which promotes the desolvation of hydrated Zn ions and inhibits the side reactions.
Bin Li   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

IR Spectroscopic Studies on Water Confined in an Isoreticular MOF Series–Influence of the Metal and Linker Functionality

open access: yesAdvanced Materials Interfaces
Mono‐ and bimetallic MOF‐74 samples with different ratios of Mg2+ and Ni2+ (9:1, 7:3, and 1:1), as well as Ni‐MOF‐74 analogs with different pore sizes and functionalities, were loaded with water through the exposure to a controlled relative humidity.
Tabea C. V. Haug   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Order matters: The impact of plyometric exercise sequencing on sprint, reactive agility, and ball speed in adolescent tennis players

open access: yesTurkish Journal of Kinesiology
This research aimed to determine the effects of different ordered plyometric exercises on sprint, reactive agility, and ball speed in adolescent tennis players.
Dilan Kızıl   +2 more
doaj   +1 more source

Group Order Logic

open access: yes2025 40th Annual ACM/IEEE Symposium on Logic in Computer Science (LICS)
We introduce an extension of fixed-point logic ($\mathsf{FP}$) with a group-order operator ($\mathsf{ord}$), that computes the size of a group generated by a definable set of permutations. This operation is a generalization of the rank operator ($\mathsf{rk}$). We show that $\mathsf{FP} + \mathsf{ord}$ constitutes a new candidate logic for the class of
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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