Results 61 to 70 of about 213,968 (259)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Self-assembly of hierarchically ordered structures in DNA nanotube systems

New Journal of Physics, 2016
The self-assembly of molecular and macromolecular building blocks into organized patterns is a complex process found in diverse systems over a wide range of size and time scales.
Martin Glaser, Jörg Schnauß, Teresa Tschirner, B U Sebastian Schmidt, Maximilian Moebius-Winkler, Josef A Käs, David M Smith   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Unusual ordered phases with long periodic stacking structures in an additively manufactured TiAl alloy

Materials Research Letters, 2020
In the present work, we have extensively examined the alternative-band microstructure of a Ti-47Al-2Cr-2Nb alloy fabricated via direct laser deposition by means of high resolution transmission electron microscopy and selected area electron diffraction ...
Xinyu Zhang, Chuanwei Li, Qing Wang, Mengyao Zheng, Zhenhua Ye, Jianfeng Gu   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Effect of Ultrasound Treatment Time on Physicochemical and Structural Properties of Lotus Root Starch [PDF]

Shipin Kexue
This study investigated the effects of different durations of ultrasound treatment (0, 10, 20, 30, 40 and 50 min) on the gelatinization, rheological properties, crystal structure, short-range ordered structure, and microstructure of lotus root starch (LS)
LIAO Xueqin, WANG Nan, HU Rong, XUE Bingjie, ZHANG Fusheng, ZHENG Jiong
doaj   +1 more source

G1-Structures of second order

Publicacions Matemàtiques, 1992
The author introduces the notion of a \(G_ 1\)-structure of order 2 (briefly \(G^ 2_ 1\)- structures.) Let us recall that a \(G_ 1\)- structure on a manifold \(V\) is defined by an endomorphism \(J\) of the tangent bundle \(TV\) with constant rank and such that \(J^ 2 = 0\). Then a \(G^ 2_ 1\)-structure is a generalization of almost tangent structures.
openaire   +6 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source